Chiral diselenide ligands for the asymmetric copper-catalyzed conjugate addition of Grignard reagents to enones

被引：78

作者：

Braga, AL ^{[1
]}

Silva, SJN

Lüdtke, DS

Drekener, RL

Silveira, CC

Rocha, JBT

Wessjohann, LA

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Inst Plant Biochem, D-06120 Halle An Der Saale, Saale, Germany

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 41期

关键词：

diselenide; catalyst; conjugate addition; chiral ligand;

D O I：

10.1016/S0040-4039(02)01713-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The copper-catalyzed conjugate addition of Grignard reagents to enones in the presence of chiral diselenide oxazoline ligands has been studied and found to provide good yields and useful levels of asymmetric induction. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：7329 / 7331

页数：3

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