Geometric calibration method based micro-CT system for small-animal imaging

被引:0
作者
Hu, Zhanli [1 ,2 ]
Zou, Jing [1 ,2 ]
Gui, Jianbao [1 ,2 ]
Rong, Junyan [1 ,2 ]
Li, Yanming [1 ,2 ]
Zheng, Hairong [1 ,2 ]
机构
[1] Chinese Acad Sci, Paul C Lauterbur Res Ctr Biomed Imaging, Shenzhen Inst Adv Technol, Inst Biomed & Hlth Engn, Shenzhen, Peoples R China
[2] Chinese Acad Sci, Key Lab Biomed Informat & Hlth Engn, Beijing 100864, Peoples R China
来源
2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010) | 2010年
关键词
x-ray; micro-CT; geometric calibration; smallanimal imaging; CONE-BEAM TOMOGRAPHY; FLAT-PANEL DETECTOR; MICROTOMOGRAPHY; PARAMETERS; SCANNER;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Small-animal imaging technology has been rapidly developed for longitudinal screening of laboratory animals raised with disease developments or genetic manipulations. Micro-CT is a noninvasive imaging modality used to assess morphology and function in small-animal imaging. Geometric calibration involves the estimation of a set of parameters that describes the geometry of such systems, and is essential for accurate image reconstruction. Noo F et al (2000) have proposed a new analytic method for calibration of x-ray cone-beam scanners that use a circular path for the cone vertex. In this paper, we use this analytic calibration method for the estimation of the geometric parameters of a practical small-animal imaging micro-CT system. We improve calibration phantom of this method in order to make it more suitable for micro-CT system. The overall performance of the micro-CT system is demonstrated in some results of small-animal imaging. The projection images demonstrated that the adopt method is robust and easy to implement with high precision.
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页数:4
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