Follicular dendritic cells in lymph nodes store infectious HIV-1 despite antiretroviral therapy

被引:2
作者
Dutartre, Helene [1 ]
机构
[1] Univ Lyon 1, Inserm,U1111,CNRS,UMR5308,LabEx ECOFECT Ecoevolut, Ecole Normale Super Lyon,Ctr Int Rech Infectiol, Equipe Oncogenese Retrovirale,Equipe Labellisee, 46 Allee Italie, F-69007 Lyon, France
来源
M S-MEDECINE SCIENCES | 2016年 / 32卷 / 10期
关键词
IMMUNODEFICIENCY-VIRUS TYPE-1; HELPER-CELLS; REPLICATION; LATENCY;
D O I
10.1051/medsci/20163210004
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:803 / 805
页数:3
相关论文
共 50 条
  • [41] Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy
    Niessl, Julia
    Baxtera, Amy E.
    Morou, Antigoni
    Brunet-Ratnasingham, Elsa
    Sannier, Geremy
    Gendron-Lepage, Gabrielle
    Richard, Jonathan
    Delgado, Gloria-Gabrielle
    Brassard, Nathalie
    Turcotte, Isabelle
    Fromentin, Rerni
    Bernard, Nicole F.
    Chomont, Nicolas
    Routy, Jean-Pierre
    Dube, Mathieu
    Finzi, Andres
    Kaufmann, Daniel E.
    [J]. EBIOMEDICINE, 2020, 54
  • [42] Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption
    Gondim, Marcos V. P.
    Sherrill-Mix, Scott
    Bibollet-Ruche, Frederic
    Russell, Ronnie M.
    Trimboli, Stephanie
    Smith, Andrew G.
    Li, Yingying
    Liu, Weimin
    Avitto, Alexa N.
    DeVoto, Julia C.
    Connell, Jesse
    Fenton-May, Angharad E.
    Pellegrino, Pierre
    Williams, Ian
    Papasavvas, Emmanouil
    Lorenzi, Julio C. C.
    Salantes, D. Brenda
    Mampe, Felicity
    Monroy, M. Alexandra
    Cohen, Yehuda Z.
    Heath, Sonya
    Saag, Michael S.
    Montaner, Luis J.
    Collman, Ronald G.
    Siliciano, Janet M.
    Siliciano, Robert F.
    Plenderleith, Lindsey J.
    Sharp, Paul M.
    Caskey, Marina
    Nussenzweig, Michel C.
    Shaw, George M.
    Borrow, Persephone
    Bar, Katharine J.
    Hahn, Beatrice H.
    [J]. SCIENCE TRANSLATIONAL MEDICINE, 2021, 13 (576)
  • [43] CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection
    Baiyegunhi, Omolara O.
    Mann, Jaclyn
    Khaba, Trevor
    Nkosi, Thandeka
    Mbatha, Anele
    Ogunshola, Funsho
    Chasara, Caroline
    Ismail, Nasreen
    Ngubane, Thandekile
    Jajbhay, Ismail
    Pansegrouw, Johan
    Dong, Krista L.
    Walker, Bruce D.
    Ndung'u, Thumbi
    Ndhlovu, Zaza M.
    [J]. NATURE COMMUNICATIONS, 2022, 13 (01)
  • [44] Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1
    Miller, Shannon M.
    Miles, Brodie
    Guo, Kejun
    Folkvord, Joy
    Meditz, Amie L.
    McCarter, Martin D.
    Levy, David N.
    MaWhinney, Samantha
    Santiago, Mario L.
    Connick, Elizabeth
    [J]. JOURNAL OF VIROLOGY, 2017, 91 (17)
  • [45] Effect of lithium on HIV-1 expression and proviral reservoir size in the CD4+ T cells of antiretroviral therapy suppressed patients
    Puertas, Maria C.
    Salgado, Maria
    Moron-Lopez, Sara
    Ouchi, Dan
    Munoz-Moreno, Jose A.
    Molto, Jose
    Clotet, Bonaventura
    Martinez-Picado, Javier
    [J]. AIDS, 2014, 28 (14) : 2157 - 2159
  • [46] Initiation of Antiretroviral Therapy (ART) at Different Stages of HIV-1 Disease Is Not Associated with the Proportion of Exhausted CD8+ T Cells
    Jensen, Sanne Skov
    Fomsgaard, Anders
    Larsen, Tine Kochendorf
    Tingstedt, Jeanette Linnea
    Gerstoft, Jan
    Kronborg, Gitte
    Pedersen, Court
    Karlsson, Ingrid
    [J]. PLOS ONE, 2015, 10 (10):
  • [47] Intensification of Antiretroviral Therapy with a CCR5 Antagonist in Patients with Chronic HIV-1 Infection: Effect on T Cells Latently Infected
    Gutierrez, Carolina
    Diaz, Laura
    Vallejo, Alejandro
    Hernandez-Novoa, Beatriz
    Abad, Maria
    Madrid, Nadia
    Dahl, Viktor
    Rubio, Rafael
    Moreno, Ana M.
    Dronda, Fernando
    Luis Casado, Jose
    Navas, Enrique
    Jesus Perez-Elias, Maria
    Zamora, Javier
    Palmer, Sarah
    Munoz, Eduardo
    Angeles Munoz-Fernandez, Maria
    Moreno, Santiago
    [J]. PLOS ONE, 2011, 6 (12):
  • [48] In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy
    Applegate, Tanya Lynn
    Birkett, Donald John
    Mcintyre, Glen John
    Jaramillo, Angel Belisario
    Symonds, Geoff
    Murray, John Michael
    [J]. RETROVIROLOGY, 2010, 7
  • [49] SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells
    Ayinde, Diana
    Bruel, Timothee
    Cardinaud, Sylvain
    Porrot, Francoise
    Prado, Julia G.
    Moris, Arnaud
    Schwartz, Olivier
    [J]. JOURNAL OF VIROLOGY, 2015, 89 (14) : 6994 - 7006
  • [50] Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice
    Ventura, John D.
    Beloor, Jagadish
    Allen, Edward
    Zhang, Tongyu
    Haugh, Kelsey A.
    Uchil, Pradeep D.
    Ochsenbauer, Christina
    Kieffer, Collin
    Kumar, Priti
    Hope, Thomas J.
    Mothes, Walther
    [J]. PLOS PATHOGENS, 2019, 15 (12)