1-Substituted derivatives of 2-phenylpyrrolidine-2-carboxamide

被引:7
作者
Tamazyan, R
Karapetyan, H
Martirosyan, A
Hovhannesyan, V
Gasparyan, S
机构
[1] Natl Acad Sci RA, Mol Struct Res Ctr, Yerevan 375014, Armenia
[2] Natl Acad Sci RA, Inst Fine Organ Chem, Yerevan 375014, Armenia
来源
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2002年 / 58卷
关键词
D O I
10.1107/S0108270102008636
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The structures of two potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitors (NNRTI), namely 1-(2-chlorobenzoyl)-2-phenylpyrrolidine-2-carboxamide, C18H17ClN2O2, and 1-(2-furoyl)2-phenylpyrrolidine-2-carboxamide, C16H16N2O3, have been investigated by X-ray diffraction and the butterfly-like conformation established in each case. The pyrrolidine ring has the same half-chair conformation in both structures.
引用
收藏
页码:o386 / o388
页数:3
相关论文
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    Tamazyan, R
    Martirosyan, A
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    Gasparyan, S
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