Continuous Biocatalysis in Environmentally-Friendly Media: A Triple Synergy for Future Sustainable Processes

被引:57
作者
Guajardo, Nadia [1 ,3 ]
Dominguez de Maria, Pablo [2 ,4 ]
机构
[1] Univ Tecnol Metropolitana, Programa Inst Fomento Investigac, Desarrollo Innovac, Ignacio Valdivieso 2409 San Joaquin, Santiago, Chile
[2] Sustainable Momentum, Canary Is, Spain
[3] Univ Tecnol Metropolitana, Programa Inst Fomento Invest Desarrollo & Innovac, Ignacio Valdivieso 2409, Santiago, Chile
[4] Sustainable Momentum SL, Ave Ansite 3,4-6, Las Palmas Gran Canaria 35011, Canary Is, Spain
关键词
Biocatalysis; Continuous bioreactor; Environmentally-friendly media; Sustainable processes; DEEP-EUTECTIC-SOLVENTS; PACKED-BED REACTOR; ENZYMATIC-SYNTHESIS; CONTINUOUS-FLOW; LIPASE; STABILITY; WATER; IMMOBILIZATION; OXIDATION; GREEN;
D O I
10.1002/cctc.201900773
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Enzyme catalysis (biocatalysis) is a mature strategy to perform organic synthesis with high selectivity and under mild reaction conditions. However, despite their origin and biodegradability, the simple use of enzymes is not sufficient to validate a process as green or sustainable. To reinforce the value that biocatalysis may offer, enzymatic processes can be established in environmentally-friendly media, such as water, neoteric solvents (e. g. deep-eutectic-solvents, DES), biogenic solvents (e. g. 2-MeTHF or terpenes), or even solvent-free systems (if substrates allow that). Furthermore, these options can be conducted in continuous biocatalytic processes, which are more efficient and sustainable. Hence, a triple synergy is generated, and very promising environmentally-friendly options can be envisaged. This conceptual paper discusses these alternatives, providing relevant, recently reported, successful examples.
引用
收藏
页码:3128 / 3137
页数:10
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