Novel convenient one-pot method for the synthesis of indoloquinolines

被引：5
|
作者：
Aksenov, N. A. [1 ]
Gasanova, A. Z. [1 ]
Abakarov, G. M. [2 ]
Aksenova, I., V [1 ]
Aksenov, A., V [1 ]
机构：
[1] North Caucasus Fed Univ, 1A Ul Pushkina, Stavropol 355009, Russia
[2] Dagestan State Tech Univ, 70 Ul Imama Shamilya, Makhachkala 367010, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2019年 / 68卷 / 04期
基金：
俄罗斯科学基金会;
关键词：
Fischer indole synthesis; isocryptolepine; reduction; one-pot synthesis; indole; Cryptolepis Sanguinolenta; BIOLOGICAL-ACTIVITIES; ISOCRYPTOLEPINE; ALKALOIDS; CRYPTOLEPINE; CRYPTOSANGUINOLENTINE; CRYPTOTACKIEINE; ROUTE; DERIVATIVES;
D O I：
10.1007/s11172-019-2493-4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel one-pot method based on the sequence of the Fisher reaction between nitroacetophenone and phenylhydrazines, the reduction with metallic tin directly in polyphosphoric acid, and acylation has been developed for the synthesis of indoloquinolines. The obtained indolo-[3,2-c]quinolines are precursors of the analogs of isocryptolepine alkaloid.
引用
收藏
页码：836 / 840
页数：5
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