Cytotoxicity of CdSe-based quantum dots incorporated in glass nanoparticles evaluated using human keratinocyte HaCaT cells

被引：13

作者：

Ando, Masanori ^{[1
]}

Horie, Masanori ^{[2
]}

Akazawa-Ogawa, Yoko ^{[2
]}

Hagihara, Yoshihisa ^{[2
]}

Murase, Norio ^{[3
]}

Shigeri, Yasushi ^{[2
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, Biomed Res Inst, Ikeda, Osaka, Japan

[2] Natl Inst Adv Ind Sci & Technol, Hlth Res Inst, Ikeda, Osaka, Japan

[3] Natl Inst Adv Ind Sci & Technol, Res Inst Electrochem Energy, Ikeda, Osaka, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2016年 / 80卷 / 01期

关键词：

CdSe; cytotoxicity; glass; polymer; quantum dot; BIOLOGICAL APPLICATIONS; TOXICITY ASSESSMENT; CELLULAR UPTAKE; IN-VITRO; PARTICLES;

D O I：

10.1080/09168451.2015.1069702

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

CdSe quantum dots (QDs) are potential fluorescent reagents, but leakage of Cd and Se often induces cytotoxicity. Here we prepared CdSe-based QDs with glass to reduce their leakage and examined their cytotoxicity using keratinocyte cells. The cytotoxicity of the QDs with glass was obviously lower than that of the commercial QDs with polymer, suggesting their safety for biological applications.

引用

页码：210 / 213

页数：4

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