B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation

被引:57
作者
Vergroesen, Rochelle D. [1 ]
Slot, Linda M. [1 ]
Hafkenscheid, Lise [1 ]
Koning, Marvyn T. [2 ]
van der Voort, Ellen I. H. [1 ]
Grooff, Christine A. [1 ]
Zervakis, George [2 ]
Veelken, Hendrik [2 ]
Huizinga, Tom W. J. [1 ]
Rispens, Theo [3 ]
Scherer, Hans U. [1 ]
Toes, Rene E. M. [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Rheumatol, POB 9600, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ, Med Ctr, Dept Hematol, Leiden, Netherlands
[3] Acad Med Ctr, Sanquin Res & Landsteiner Lab, Dept Immunopathol, Amsterdam, Netherlands
关键词
D O I
10.1136/annrheumdis-2017-212052
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:955 / +
页数:4
相关论文
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