Transcranial Magnetic and Direct Current Stimulation in Children

被引:101
作者
Hameed, Mustafa Q. [1 ,2 ,3 ]
Dhamne, Sameer C. [1 ,2 ]
Gersner, Roman [1 ,2 ]
Kaye, Harper L. [1 ,2 ]
Oberman, Lindsay M. [4 ,5 ,6 ]
Pascual-Leone, Alvaro [7 ,8 ,9 ]
Rotenberg, Alexander [1 ,2 ]
机构
[1] Boston Childrens Hosp, Harvard Med Sch, Dept Neurol, Div Epilepsy & Clin Neurophy,Neuromodulat Program, 300 Longwood Ave, Boston, MA 02115 USA
[2] Boston Childrens Hosp, FM Kirby Neurobiol Ctr, Harvard Med Sch, Dept Neurol, 300 Longwood Ave, Boston, MA 02115 USA
[3] Boston Childrens Hosp, Harvard Med Sch, Dept Neurosurg, Boston, MA 02115 USA
[4] Brown Univ, EP Bradley Hosp, Neuroplast & Autism Spectrum Disorder Program, Providence, RI 02912 USA
[5] Brown Univ, EP Bradley Hosp, Dept Psychiat & Human Behav, Providence, RI 02912 USA
[6] Brown Univ, Warren Alpert Med Sch, Providence, RI 02912 USA
[7] Beth Israel Deaconess Med Ctr, Harvard Med Sch, Berenson Allen Ctr Noninvas Brain Stimulat, Boston, MA 02215 USA
[8] Beth Israel Deaconess Med Ctr, Harvard Med Sch, Div Cognit Neurol, Boston, MA 02215 USA
[9] Univ Autonoma Barcelona, Inst Guttmann, Barcelona, Spain
关键词
Transcranial stimulation in children; TMS; tDCS; GABA; Cortical inhibition; Cortical excitability; THETA-BURST STIMULATION; AUTISM SPECTRUM DISORDER; LONG-TERM POTENTIATION; MEDIATED MOTOR INHIBITION; HIGH-FUNCTIONING AUTISM; DEEP BRAIN-STIMULATION; CEREBRAL-PALSY; CORTICAL EXCITABILITY; SYNAPTIC PLASTICITY; DEVELOPMENTAL SWITCH;
D O I
10.1007/s11910-017-0719-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Promising results in adult neurologic and psychiatric disorders are driving active research into transcranial brain stimulation techniques, particularly transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), in childhood and adolescent syndromes. TMS has realistic utility as an experimental tool tested in a range of pediatric neuropathologies such as perinatal stroke, depression, Tourette syndrome, and autism spectrum disorder (ASD). tDCS has also been tested as a treatment for a number of pediatric neurologic conditions, including ASD, attentiondeficit/hyperactivity disorder, epilepsy, and cerebral palsy. Here, we complement recent reviews with an update of published TMS and tDCS results in children, and discuss developmental neuroscience considerations that should inform pediatric transcranial stimulation.
引用
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页数:15
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