Hydrogenation of pyrrole derivatives .1. Hydrogenations over palladium

被引：23

作者：

Hegedus, L ^{[1
]}

Mathe, T ^{[1
]}

Tungler, A ^{[1
]}

机构：

[1] TECH UNIV BUDAPEST,HUNGARIAN ACAD SCI,ORGAN CHEM TECHNOL RES GRP,H-1521 BUDAPEST,HUNGARY

来源：

APPLIED CATALYSIS A-GENERAL | 1996年 / 143卷 / 02期

关键词：

heterogeneous catalytic hydrogenation; 1-methyl-2-pyrrolidine ethanol; palladium catalyst;

D O I：

10.1016/0926-860X(96)00094-4

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The heterogeneous catalytic hydrogenation of 1-methyl-2-pyrrole ethanol resulted in 1-methyl-2-pyrrolidine ethanol, an important and valuable pharmaceutical intermediate. In non-acidic medium, with carbon supported palladium catalyst, applying solvent mixtures and mild reaction conditions (6 bar, 80 degrees C) high conversion and selectivity were obtained. This hydrogenation is part of a newly developed and industrially feasible synthesis.

引用

页码：309 / 316

页数：8

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