Lentinus edodes and Auricularia auricula are the first and second largest edible fungi in China with high Lentinusnutritional anedodes andmedicinal Auriculariavalues. Researchauricula areabou the firstphytochemicalsand secondof L.largestedodes edibleand A.fungiauriculain Chinamainlyw thfocuseshigh onnutritionl polysaccharids,and medicinalother values.phytochemicalsResearch reaboutnot fullyphytochemcalsstudied. ofL.Phytochemicalsedodes andof A.L. auriculaedodes andmaA.nly auriculafocuses onwere polysacchries,investigated by otherultra-ighphytochemicalsperformancear notliquid fully studiedchromatograpPhy tandeochemicalshybridof L. eodesquadrupole-orbitrpandA. auriculamass were investigated by ultra-high performance liquid chromatography tandem hybrid quadrupole-orbitrap mass spectrometry (UPLC-Q-Exactive-Orbitrap MS). Twenty-three compounds were identifiiied inL. edodes, mainly including amino acids and analogs,llflavonoids, nucleosides and analog, phnols and steroids. Twenty-nine spectrometry (UPLC-Q-Exactive-Orbitrap MS). Twenty-thre compounds were identified in L. edodes, mainly includingcompounds aminowere acidsidentifiiianed inA.analogs, auricula,fl avonoids,mainly includingnucleosides aminoand acidsanalogs,and phenolsanalogs, and nucleosidessteroids. andTwenty-nineanalogs, llflcompoundsavonoids andwere phenols.identif iedTherein A.are 9auricula,common mainlyingredientsincludingof L.aminedodesacidsand andA. nalogs,auricula, inudingnucleosides4 ndamino analogs,acids flandavooidsanalogs, and2 llflphenols.avonoids, There2 arnucle osides9 commonand aalogsingredietsand 1of L.phenol.edod 2022 Beijing Academy of Food Science Publishing services by Elsevir BV on behalf of KeAi (c) 2022 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co Ltd This is an open access article under the CC BYNCND license Communications Co Ltd This s an open acss article under he CC BY NC ND license Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommonsorg/licenses/byncnd/40/) (http//c eati eco o so g/lice ses/by c d/40/) (http://creativecommons.org/licenses/by-nc-nd/4.0/).