Systemic Side Effects of Antiviral Therapy in a Patient with Acute Retinal Necrosis

被引：4
作者：
Guney, Esra [1 ]
Akcay, Betul Ilkay Sezgin [1 ]
Erdogan, Gurkan [1 ]
Unlu, Cihan [1 ]
Bozkurt, Kansu [1 ]
Onur, Umut [2 ]
机构：
[1] Umraniye Training & Res Hosp, Dept Ophthalmol, Istanbul, Turkey
[2] Bakirkoy Training & Res Hosp, Dept Ophthalmol, Istanbul, Turkey
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 2014年 / 22卷 / 03期
关键词：
Acute retinal necrosis; acyclovir; herpes virus; side effects; valacyclovir;
D O I：
10.3109/09273948.2013.833632
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To report a case of Acute Retinal Necrosis (ARN)-developed nephrotoxicity during intravenous acyclovir treatment and toxic hepatitis during oral valacyclovir treatment. Design: Interventional case report. Methods: Retrospective chart review. Results: A 45-year-old male with ARN treated with intravenous acyclovir developed nephrotoxicity. After switching to oral valacyclovir, toxic hepatitis developed. Both renal and liver function tests returned to normal levels after drug cessation Conclusions: Although rare, clinicians should be aware of the potential nephrotoxic and hepatotoxic side effects of antiviral therapy during ARN treatment.
引用
收藏
页码：233 / 235
页数：3
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