High-Density Peptide Arrays with Combinatorial Laser Fusing

被引:17
作者
Maerkle, Frieder [1 ]
Loeffler, Felix F. [1 ]
Schillo, Sebastian [1 ]
Foertsch, Tobias [1 ]
Muenster, Bastian [1 ]
Striffler, Jakob [1 ]
Schirwitz, Christopher [1 ]
Bischoff, F. Ralf [2 ]
Breitling, Frank [1 ]
Nesterov-Mueller, Alexander [1 ]
机构
[1] Karlsruhe Inst Technol, D-76344 Eggenstein Leopoldshafen, Germany
[2] German Canc Res Ctr, D-69120 Heidelberg, Germany
基金
欧洲研究理事会;
关键词
PARALLEL CHEMICAL SYNTHESIS; PATTERNS;
D O I
10.1002/adma.201305759
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Combinatorial laser fusing is a new method to produce high-density peptide arrays with feature sizes as small as 10 mu m. It combines the high spot densities achieved by lithographic methods with the cost-efficiency of biofunctional xerography. The method is also adapted for other small molecules compatible with solid phase synthesis.
引用
收藏
页码:3730 / 3734
页数:5
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