Helicobacter pylori-negative Differentiated Adenocarcinoma of the Stomach

被引：1

作者：

Nagaya, Tadanobu ^{[1
,2
]}

Tanaka, Naoki ^{[2
,3
]}

Iwaya, Yugo ^{[1
,2
]}

Jimbo, Yoko ^{[1
]}

Tatai, Toshiharu ^{[1
]}

Ito, Tetsuya ^{[1
]}

Seki, Ayako ^{[1
]}

Suzawa, Kenichi ^{[1
]}

Ochi, Yasuhide ^{[1
]}

Hara, Etsuo ^{[1
]}

Takata, Manabu ^{[4
]}

Otsuki, Toshiaki ^{[5
]}

Iwaya, Mai ^{[5
]}

Hosaka, Noriko ^{[5
]}

Arakura, Norikazu ^{[2
]}

Tanaka, Eiji ^{[2
]}

Hasebe, Osamu ^{[1
]}

机构：

[1] Nagano Municipal Hosp, Dept Gastroenterol, Nagano, Japan

[2] Shinshu Univ, Sch Med, Dept Gastroenterol, Matsumoto, Nagano, Japan

[3] Shinshu Univ, Grad Sch Med, Dept Metab Regulat, Matsumoto, Nagano, Japan

[4] Nagano Municipal Hosp, Dept Surg, Nagano, Japan

[5] Nagano Municipal Hosp, Div Clin Pathol, Nagano, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 22期

关键词：

early gastric cancer; Helicobacter pylori; differentiated adenocarcinoma; ESD; mucin phenotype; EARLY GASTRIC-CANCER; JAPANESE; EXPRESSION; INFECTION;

D O I：

10.2169/internalmedicine.54.4400

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 58-year-old Japanese man was diagnosed with differentiated adenocarcinoma of the stomach. Histological findings of the resected specimen revealed well-to moderately-differentiated tubular adenocarcinoma (tub1, tub2), 13 mm in diameter, which invaded into the submucosa (SM1, 300 mu m) and lymphovascular lumen (ly1). Serum antibody against Helicobacter pylori (Hp) and the C-13-urea breath test were negative, and there were no atrophic changes in the tumor-adjacent mucosa. The immunohistochemical analysis showed that gastric mucin (MUC5AC) was strongly positive and intestinal mucin (MUC2) was weakly and partially positive. According to these results, the final diagnosis of Hp-negative well-differentiated early gastric cancer was made.

引用

页码：2857 / 2862

页数：6

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