N-acylazinium salts: A new source of iminium ions for Ugi-type processes

被引：75

作者：

Diaz, JL

Miguel, M

Lavilla, R

机构：

[1] Univ Barcelona, Barcelona 08028, Spain

[2] Univ Barcelona, Fac Pharm, Lab Organ Chem, Barcelona 08028, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 10期

关键词：

D O I：

10.1021/jo049823n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A multicomponent reaction involving the interaction of azines (quinolines, isoquinolines, and phenanthridine) with activating agents (chloroformates, acid halides, and sulfonyl halides), isocyanides, and water is described. The products of this process, alpha-carbamoylated-1,2-dihydroazines, are the result of the addition of the isocyanide partner to the N-acylazinium salt formed in situ. This represents a new source of iminium ion equivalents for Ugi-type reactions.

引用

页码：3550 / 3553

页数：4

共 39 条

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