Towards a mechanistic understanding of the human subcortex

被引：71

作者：

Forstmann, Birte U. ^{[1
,2
]}

de Hollander, Gilles ^{[1
,2
]}

van Maanen, Leendert ^{[3
]}

Alkemade, Anneke ^{[1
,2
]}

Keuken, Max C. ^{[1
,2
]}

机构：

[1] Univ Amsterdam, Amsterdam Brain & Cognit Ctr, Nieuwe Achtergracht 129B, NL-1018 WT Amsterdam, Netherlands

[2] Royal Netherlands Acad Arts & Sci, Netherlands Inst Neurosci, Inst, Meibergdreef 47, NL-1105 BA Amsterdam, Netherlands

[3] Univ Amsterdam, Psychol Methods Dept, NL-1018 WT Amsterdam, Netherlands

来源：

NATURE REVIEWS NEUROSCIENCE | 2017年 / 18卷 / 01期

基金：

欧洲研究理事会;

关键词：

DEEP BRAIN-STIMULATION; TO-NOISE RATIO; HIGH-FIELD MRI; SUBTHALAMIC NUCLEUS; BASAL GANGLIA; MAGNETIC-RESONANCE; DECISION-MAKING; IN-VIVO; MULTIPLE-SCLEROSIS; HUMAN HYPOTHALAMUS;

D O I：

10.1038/nrn.2016.163

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The human subcortex is a densely populated part of the brain, of which only 7% of the individual structures are depicted in standard MRI atlases. In vivo MRI of the subcortex is challenging owing to its anatomical complexity and its deep location in the brain. The technical advances that are needed to reliably uncover this 'terra incognita' call for an interdisciplinary human neuroanatomical approach. We discuss the emerging methods that could be used in such an approach and the incorporation of the data that are generated from these methods into model-based cognitive neuroscience frameworks.

引用

页码：57 / 65

页数：9

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