Three new diterpenoid alkaloids from the roots of Aconitum duclouxii

被引:20
作者
Yin, Tian-Peng [1 ]
Cai, Le [1 ]
He, Jian-Min [2 ]
Dong, Jian-Wei [1 ]
Fang, Hai-Xian [1 ]
Zhou, Hao [1 ]
Ding, Zhong-Tao [1 ]
机构
[1] Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Peoples R China
[2] Baoshan Univ, Sch Resource & Environm, Baoshan 678000, Peoples R China
关键词
Aconitum duclouxii; biological activity; ducloudines C-E; diterpenoid alkaloids;
D O I
10.1080/10286020.2014.881802
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new C-19-diterpenoid alkaloids, ducloudines C (1), D (2), and E (3), were isolated from the roots of Aconitum duclouxii. Their structures were established on the basis of extensive spectroscopic analyses. Ducloudine C (1) is the first aconitine-type C-19-diterpenoid alkaloid with a C=O group at C-3 and a C=C bond between C-1 and C-2. All compounds were tested for their biological activities against one pathogenic fungi and two pathogenic bacteria.
引用
收藏
页码:345 / 350
页数:6
相关论文
共 12 条
[1]  
[Anonymous], 1982, CHIN J ORG CHEM
[2]   Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits [J].
Carpinella, MC ;
Ferrayoli, CG ;
Palacios, SM .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (08) :2922-2927
[3]  
Ding L.S., 1989, NAT PROD RES DEV, V1, P6
[4]  
Pelletier S.W., 1984, The Alkaloids: Chemical and Biological Perspectives, V2, P206
[5]  
PELLETIER SW, 1976, J AM CHEM SOC, V98, P2626, DOI 10.1021/ja00425a035
[6]  
Peng CS, 2005, CHINESE J ORG CHEM, V25, P1235
[7]  
People's Government of Dali Bai Autonomous Prefecture, 1991, NAT RES CHIN MED MAT, P77
[8]  
Wang C Y, 1984, Yao Xue Xue Bao, V19, P445
[9]   A pharmacophylogenetic study of Aconitum L. (Ranunculaceae) from China [J].
Xiao, PG ;
Wang, FP ;
Gao, F ;
Yan, LP ;
Chen, DL ;
Liu, Y .
ACTA PHYTOTAXONOMICA SINICA, 2006, 44 (01) :1-46
[10]  
Xie G. B., 1997, HETEROCYCLES, V3, P631