Current Results of Surgical Aortic Valve Replacement: Insights From the German Aortic Valve Registry

被引:36
作者
Holzhey, David [1 ]
Mohr, Friedrich W.
Walther, Thomas
Moellmann, Helge
Beckmann, Andreas
Koetting, Joachim
Figulla, Hans Reiner
Cremer, Jochen
Kuck, Karl-Heinz
Lange, Ruediger
Sack, Stefan
Schuler, Gerhard
Beyersdorf, Friedhelm
Boehm, Michael
Heusch, Gerd
Meinertz, Thomas
Neumann, Till
Papoutsis, Konstantinos
Schneider, Steffen
Welz, Armin
Hamm, Christian W.
机构
[1] Heart Ctr Leipzig, D-04289 Leipzig, Germany
关键词
HIGH-RISK PATIENTS; TRANSCATHETER; IMPLANTATION; STENOSIS; MULTICENTER; PROSTHESIS; OUTCOMES; GARY;
D O I
10.1016/j.athoracsur.2015.07.090
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Conventional aortic valve replacement (AVR) remains the therapy of choice for many patients with severe aortic valve disease. The unique German Aortic Valve Registry (GARY) allows the comparison of contemporary outcomes of AVR with those of trans-catheter AVRs. We report here real-world, all-comers outcomes of AVR, including combined AVR and coronary bypass grafting (AVR+CABG). Methods. A total of 34,063 patients who received AVR (22,107 patients, 39% female; mean age 68.0 +/- 11.3 years, mean logistic European System for Cardiac Operative Risk Evaluation, 8.6%) or AVR+CABG (11,956 patients, 28% female; mean age 72.6 +/- 7.8 years, mean logistic European System for Cardiac Operative Risk Evaluation, 10.7%) between 2011 and 2013 were analyzed and followed up to assess the 1-year outcome. Results. In-hospital mortality was 2.3% for AVR and 4.1% for AVR+CABG. Other important outcome variables include stroke (AVR, 1.2%; AVR+CABG, 1.9%) and new pacemaker implantation (AVR, 4.4%; AVR+CABG, 3.6%). Survival at 1 year was 93.2% for AVR and 89.4% for AVR+CABG. Total stroke rates at 1 year were 1.6% for AVR and 2.0% AVR+CABG. Quality of life assessment indicated that most patients were in New York Heart Association Functional Classification I or II (AVR, 86%; AVR+CABG, 84%) and that they were satisfied with the overall postoperative course (AVR, 88%; AVR+CABG, 87%). Conclusions. Contemporary surgical AVR yields excellent outcomes with low in-hospital mortality, a low overall complication rate, and good 1-year outcome for all risk groups. Accordingly, conventional AVR remains an important therapeutic option for many patients. (C) 2016 by The Society of Thoracic Surgeons
引用
收藏
页码:658 / 666
页数:9
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