Photon-modulated changes of cell attachments on poly(spiropyran-co-methyl methacrylate) membranes

被引：71

作者：

Higuchi, A ^{[1
]}

Hamamura, A ^{[1
]}

Shindo, Y ^{[1
]}

Kitamura, H ^{[1
]}

Yoon, BO ^{[1
]}

Mori, T ^{[1
]}

Uyama, T ^{[1
]}

Umezawa, A ^{[1
]}

机构：

[1] Seikei Univ, Dept Appl Chem, Musashino, Tokyo 1808633, Japan

来源：

BIOMACROMOLECULES | 2004年 / 5卷 / 05期

关键词：

D O I：

10.1021/bm049737x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Spiropyran is a photoresponsive molecule, and nonionic spiropyran is reversibly changed by UV irradiation to a hydrophilic polar, zwitterionic merocyanine isomer, and back again by visible light irradiation. A copolymer of nitrobenzospiropyran and methyl methacrylate, poly(NSP-co-MMA) was used as a material with a photosensitive surface. UV irradiation of the photosensitive surface of poly (NSP-co-MMA)-coated glass plates decreased the water contact angles (11 +/- 1degrees) and increased diameter of a water drop relative to the unexposed surface. Light-induced detachment of platelets and mesenchymal stem (KUSA-A1) cells on poly(NSP-co-MMA)-coated glass plates was observed upon simple- and patterned-light irradiation, whereas no light-induced detachment of platelets and mesenchymal stem cells was observed on poly(methyl methacrylate)-coated glass plates. This is a result of the change from a closed nonpolar spiropyran to the polar zwitterionic merocyanine isomer induced by UV irradiation. Light-induced detachment of fibrinogen adsorbed on poly(NSP-co-MMA) coated glass plates was also observed in this investigation.

引用

页码：1770 / 1774

页数：5

共 21 条

[1] Charge-induced modification of contact angle: The secondary electrocapillary effect [J].

Digilov, R .

LANGMUIR, 2000, 16 (16) :6719-6723

[2] Photon-controlled phase partitioning of spiropyrans [J].

García, AA ;

Cherian, S ;

Park, J ;

Gust, D ;

Jahnke, F ;

Rosario, R .

JOURNAL OF PHYSICAL CHEMISTRY A, 2000, 104 (26) :6103-6107

[3] Visible light is able to regulate neurite outgrowth [J].

Higuchi, A ;

Kitamura, H ;

Shishimine, KI ;

Konishi, S ;

Yoon, BO ;

Hara, M .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2003, 14 (12) :1377-1388

[4] Serum protein adsorption and platelet adhesion on pluronic™-adsorbed polysulfone membranes [J].

Higuchi, A ;

Sugiyama, K ;

Yoon, BO ;

Sakurai, M ;

Hara, M ;

Sumita, M ;

Sugawara, S ;

Shirai, T .

BIOMATERIALS, 2003, 24 (19) :3235-3245

[5] Growth of L929 cells on polymeric films prepared by Langmuir-Blodgett and casting methods [J].

Higuchi, A ;

Tamiya, S ;

Tsubomura, T ;

Katoh, A ;

Cho, CS ;

Akaike, T ;

Hara, M .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2000, 11 (02) :149-168

[6] Creation of designed shape cell sheets that are noninvasively harvested and moved onto another surface [J].

Hirose, M ;

Kwon, OH ;

Yamato, M ;

Kikuchi, A ;

Okano, T .

BIOMACROMOLECULES, 2000, 1 (03) :377-381

[7] Light-driven motion of liquids on a photoresponsive surface [J].

Ichimura, K ;

Oh, SK ;

Nakagawa, M .

SCIENCE, 2000, 288 (5471) :1624-1626

[8] Photochromic organic-inorganic polymer hybrids from spiropyran-modified poly(N,N-dimethylacrylamide) [J].

Imai, Y ;

Adachi, K ;

Naka, K ;

Chujo, Y .

POLYMER BULLETIN, 2000, 44 (01) :9-15

[9] Axonal outgrowth of hippocampal neurons on micro-scale networks of polylysine-conjugated laminin [J].

Kam, L ;

Shain, W ;

Turner, JN ;

Bizios, R .

BIOMATERIALS, 2001, 22 (10) :1049-1054

[10]

KAMEDA M, UNPUB

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