Thromboembolic Disease After Orthopedic Trauma

被引:24
作者
Whiting, Paul S. [1 ]
Jahangir, A. Alex [2 ]
机构
[1] Univ Wisconsin, Dept Orthopaed & Rehabil, 1685 Highland Ave, Madison, WI 53705 USA
[2] Vanderbilt Univ, Med Ctr, Dept Orthopaed & Rehabil, 1215 21st Ave South,MCE South Tower,Suite 4200, Nashville, TN 37232 USA
关键词
Orthopaedic trauma; Coagulation; Deep venous thrombosis; Pulmonary embolism; Thromboprophylaxis; DEEP-VEIN THROMBOSIS; MOLECULAR-WEIGHT HEPARIN; VENOUS THROMBOEMBOLISM; MAJOR TRAUMA; PULMONARY-EMBOLISM; HYPERCOAGULABLE STATE; ACETABULAR FRACTURES; LOWER-EXTREMITY; PLASTER CAST; DATA-BANK;
D O I
10.1016/j.ocl.2015.09.002
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Orthopedic trauma results in systemic physiologic changes that predispose patients to venous thromboembolism (VTE). In the absence of prophylaxis, VTE incidence may be as high as 60%. Mechanical and pharmacologic thromboprophylaxis are effective in decreasing rates of VTE. Combined mechanical and pharmacologic thromboprophylaxis is more efficacious for decreasing VTE incidence than either regimen independently. If pharmacologic thromboprophylaxis is contraindicated, mechanical prophylaxis should be used. Patients with isolated lower extremity fractures who are ambulatory, or those with isolated upper extremity trauma, do not require pharmacologic prophylaxis in the absence of other VTE risk factors.
引用
收藏
页码:335 / +
页数:11
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