Microwave-assisted one-pot synthesis of pyrazolyl-substituted benzochroman-4-one derivatives and evaluation of their anticancer activity

被引：7

作者：

Ashok, Dongamanti ^{[1
]}

Padmavati, Kadiyala ^{[1
]}

Lakshmi, Bommidi Vijaya ^{[1
]}

Sarasija, Madderla ^{[1
]}

机构：

[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2016年 / 52卷 / 01期

关键词：

1-(1-hydroxynaphthalen-2-yl)ethanone; 1-(2-hydroxynaphthalen-2-yl)ethanone; anticancer activity; microwave irradiation; FLAVANONE; CYTOTOXICITY; DESIGN;

D O I：

10.1007/s10593-016-1824-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hybrid compounds containing both flavanone and pyrazole moieties have been synthesized from acetylnaphthols and pyrazole-4-carbaldehydes in good yields using microwave irradiation in a one-step procedure. The synthesized compounds were evaluated for their anticancer activity against four human cancer cell lines.

引用

页码：15 / 20

页数：6

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