Syntheses, mutagenicity and applied performance of 2,8-diamino-10-methoxy-5,10-dihydrophenophosphazine 10-oxide

10-Hydroxy-5,10-dihydrophenophosphazine 10-oxide (1) reacted with SOCl2, and then with MeONa in MeOH to give a methyl phosphinate (2) which can be converted to a dinitro compound 3 (62%) by nitration and the resulting dinitro compound 3 can further be converted to 2,8-diamino-10-methoxy-5, 10-dihydrophenophosphazine 10-oxide (4, 71%) by hydrogenation over Pd/C (w = 0.05). And the effect of amount of Pd/C ( w = 0.05) on the reduction was also studied. This nonmutagenic amino compound 4 (via the investigation into Salmonella/mammalian microsome assay) was also employed as diazo moiety coupling with acet-J-acid to form a diazo acid dye 5. The new dye 5 can color wool at 2% or silk at 3% o.w.f. into black one.. The investigation of the uptake of 5 and its color appearance showed that it-was assigned to an acid bluish black dye and its blackness was more excellent than that of Acid Black 10B.