Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report

被引：13
|
作者：
Torcuator, Roy [1 ]
Zuniga, Richard [1 ]
Loutfi, Randa [2 ]
Mikkelsen, Tom [1 ,3 ]
机构：
[1] Henry Ford Hlth Syst, Hermelin Brain Tumor Ctr, Dept Neurosurg, Detroit, MI 48202 USA
[2] Henry Ford Hlth Syst, Hermelin Brain Tumor Ctr, Dept Med Oncol, Detroit, MI 48202 USA
[3] Henry Ford Hlth Syst, Hermelin Brain Tumor Ctr, Dept Neurol, Detroit, MI 48202 USA
来源：
JOURNAL OF NEURO-ONCOLOGY | 2009年 / 93卷 / 03期
关键词：
Brainstem; Glioma; Diffuse chemotherapy; Bevacizumab; Irinotecan; CHILDREN; CHEMOTHERAPY; RADIOTHERAPY; TRIAL;
D O I：
10.1007/s11060-008-9782-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Diffuse brainstem glioma carries a dismal prognosis. The current cornerstone of treatment is radiation therapy. Chemotherapy appears to be ineffective and the role of this treatment in the recurrent or progressive setting is not known. Bevacizumab and irinotecan have been reported to have shown radiographic response and improvement in progression-free survival among patients with malignant supratentorial gliomas. In this paper, we report our experience in an adult patient with progressive diffuse brainstem glioma treated with bevacizumab and irinotecan.
引用
收藏
页码：409 / 412
页数：4
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