Identifying a Hyperkeratosis Signature in Autosomal Recessive Congenital Ichthyosis: Mdm2 Inhibition Prevents Hyperkeratosis in a Rat ARCI Model

被引：8
作者：
Youssef, Gehad [1 ,2 ]
Ono, Masahiro [2 ]
Brown, Stuart J. [1 ,2 ]
Kinsler, Veronica A. [1 ,3 ]
Sebire, Neil J. [4 ]
Harper, John I. [1 ,2 ]
O'Shaughnessy, Ryan F. L. [1 ,2 ]
机构：
[1] UCL, Inst Child Hlth, Livingstone Skin Res Ctr, London, England
[2] UCL, Inst Child Hlth, London, England
[3] UCL, Inst Child Hlth, Clin & Mol Genet Unit, London, England
[4] Great Ormond St Hosp Sick Children, London WC1N 3JH, England
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2014年 / 134卷 / 03期
关键词：
LAMELLAR ICHTHYOSIS; TRANSGLUTAMINASE-1; ACTIVATION; NUTLIN-3; CELLS; GENE; MICE; AKT;
D O I：
10.1038/jid.2013.374
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：858 / 861
页数：4
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