I2-catalyzed one-pot synthesis of benzofuro/thieno[2,3-b]pyrrole motifs

被引：11

作者：

Chacko, Priya ^{[1
]}

Shivashankar, Kalegowda ^{[1
]}

机构：

[1] Bangalore Univ, PG Dept Chem, Cent Coll Campus, Bangalore 560001, Karnataka, India

来源：

TETRAHEDRON | 2018年 / 74卷 / 13期

关键词：

Iodine; Benzofuran; Benzothiophene; Pyrroles; Furan; Thiophene; Thieno; COMPONENT REACTION; BENZYL HALIDES; CYCLIZATION; DERIVATIVES; ACCESS;

D O I：

10.1016/j.tet.2018.02.013

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel I-2-catalyzed one-pot multicomponent protocol for the synthesis of a variety of elusive furo[2,3-b] pyrrole and thieno[2,3-b]pyrrole libraries has been established. To date, cyclization among alkanone, hydrazine and 2-bromobenzofuran or 2-bromobenzo[b]thiophene has not been explored in one-pot. Thus, the proposed single step protocol provides a versatile alternative to existing routes for accessing useful furo[2,3-b]pyrrole and thieno[2,3-b]pyrrole libraries. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：1520 / 1526

页数：7

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