Toward a miniature endomicroscope: pixelation-free and diffraction-limited imaging through a fiber bundle

被引:90
作者
Kim, Donggyu [1 ]
Moon, Jungho [1 ]
Kim, Moonseok [1 ]
Yang, Taeseok Daniel [1 ]
Kim, Jaisoon [2 ]
Chung, Euiheon [3 ]
Choi, Wonshik [1 ]
机构
[1] Korea Univ, Dept Phys, Seoul 136701, South Korea
[2] Myongji Univ, Dept Phys, Yongin 449728, South Korea
[3] Gwangju Inst Sci & Technol, Dept Med Syst Engn, Kwangju 500712, South Korea
基金
新加坡国家研究基金会;
关键词
FOCUSING LIGHT; MULTIMODE; RESOLUTION; BIOPSY;
D O I
10.1364/OL.39.001921
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A fiber bundle is widely used for endoscopic imaging due to its direct image delivery capability. However, there exists an inevitable pixelation artifact, which limits spatial resolution to the diameter of individual fibers. In this Letter, we present a method that can eliminate this artifact and achieve diffraction-limited spatial resolution. We exploited the binary control of a digital micromirror device to measure a transmission matrix of a fiber bundle and to subsequently control mode mixing among individual fibers. In doing so, we achieved a 22 kHz scanning rate of a diffraction-limited focused spot and obtained fluorescence endoscope imaging (58 mu m x 58 mu m) with near video-rate (10.3 Hz) acquisition. Our study lays a foundation for developing an ultrathin and high-resolution microendoscope. (C) 2014 Optical Society of America
引用
收藏
页码:1921 / 1924
页数:4
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