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Comparison of three real-time PCR assays for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in young pregnant women
被引:13
|作者:
Peuchant, Olivia
[1
,2
,3
]
de Diego, Sabrina
[1
,2
]
Le Roy, Chloe
[1
,2
]
Frantz-Blancpain, Sandrine
[4
]
Hocke, Claude
[4
]
Bebear, Cecile
[1
,2
,3
]
de Barbeyrac, Bertille
[1
,2
,3
]
机构:
[1] Univ Bordeaux, USC EA Infect Humaines Mycoplasmes & Chlamydiae 3, Bordeaux, France
[2] INRA, USC EA Infect Humaines Mycoplasmes & Chlamydiae 3, Bordeaux, France
[3] Ctr Hosp Univ Bordeaux, Lab Bacteriol, Bordeaux, France
[4] Ctr Hosp Univ Bordeaux, Serv Gynecol Obstet, Bordeaux, France
关键词:
Chlamydia trachomatis;
Neisseria gonorrhoeae;
Real-time PCRs;
Vaginal swabs;
Pregnant women;
MYCOPLASMA-GENITALIUM;
VAGINAL SWABS;
TERMINATION;
PREVALENCE;
D O I:
10.1016/j.diagmicrobio.2015.09.002
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
We compared 3 commercial real-time PCR assays, the Abbott RealTime CT/NG, the cobas (R) 4800 CT/NG, and the Cepheid Xpert (R) CT/NG, for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in vaginal swabs collected prospectively from pregnant women aged <25 years. The overall agreement among 2 assays ranged from 98.9% to 995% with a kappa score between 0.94 and 0.97 for C. trachomatis. For N. gonorrhoeae, the overall agreement was 100%. All kits allowed prompt and specific results for C. trachomatis and N. gonorrhoeae in young pregnant women. (C) 2015 Elsevier Inc. All rights reserved.
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页码:335 / 337
页数:3
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