Malignant juxtaglomerular cell tumor

被引：6

作者：

Geisler, Daniel ^{[1
]}

Almutairi, Fawaz ^{[1
]}

John, Ivy ^{[1
]}

Quiroga-Garza, Gabriela ^{[1
]}

Yu, Michelle ^{[2
]}

Seethala, Raja ^{[1
]}

Bastacky, Sheldon ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Pathol, Med Ctr, 5230 Ctr Ave, Pittsburgh, PA 15232 USA

[2] Univ Pittsburgh, Dept Urol, Med Ctr, Pittsburgh, PA 15232 USA

来源：

UROLOGY CASE REPORTS | 2022年 / 45卷

关键词：

Kidney; Juxtaglomerular cell tumor; Malignant; Renin; GATA3;

D O I：

10.1016/j.eucr.2022.102176

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Juxtaglomerular cell tumors (JGCTs) are rare, typically benign neoplasms; only rare cases are clinically or histologically malignant. We herein report the histologic, immunophenotypic, and molecular features of a clinically unsuspected, diagnostically challenging case of malignant JGCT in a 23-year-old man. The diagnosis is confirmed with electron microscopy. The case is notable for its marked mitotic activity, which has not been previously reported in JGCTs, and novel finding of GATA3 immunohistochemical positivity.

引用

页数：3