Relation of body mass index and skinfold thicknesses to cardiovascular disease risk factors in children: the Bogalusa Heart Study

被引:127
作者
Freedman, David S. [1 ]
Katzmarzyk, Peter T. [2 ]
Dietz, William H. [1 ]
Srinivasan, Sathanur R. [3 ]
Berenson, Gerald S. [3 ]
机构
[1] CDC, Div Nutr Phys Act & Obes, Atlanta, GA 30341 USA
[2] Pennington Biomed Res Ctr, Baton Rouge, LA USA
[3] Tulane Univ, Sch Publ Hlth & Trop Med, Tulane Ctr Cardiovasc Hlth, New Orleans, LA USA
关键词
FAT-FREE MASS; X-RAY ABSORPTIOMETRY; BIOELECTRICAL-IMPEDANCE; METABOLIC RISK; BLOOD-PRESSURE; FOLLOW-UP; MEASUREMENT ERROR; TRICEPS SKINFOLD; OBESITY; ADIPOSITY;
D O I
10.3945/ajcn.2009.27525
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: Adverse levels of cardiovascular disease (CVD) risk factors are related to skinfold thicknesses and body mass index (BMI) among children, but the relative strengths of these associations are unknown. Objective: The objective was to determine whether the sum of the triceps and subscapular skinfold thicknesses (SF sum) is more strongly related to levels of 6 risk factors (triglycerides, LDL and HDL cholesterol, insulin, and systolic and diastolic blood pressure) than is BMI. Design: Cross-sectional analyses of schoolchildren examined in the Bogalusa Heart Study from 1981 to 1994 (n = 6866) were conducted. A risk factor summary index was derived by using principal components analysis. Results: After race, sex, study period, and age were controlled for, almost all comparisons indicated that BMI was more strongly related to risk factor levels than was the SF sum. Although the differences were generally small, many were statistically significant. Associations with the risk factor summary, for example, were r = 0.50 for BMI and r = 0.47 for SF sum (P < 0.001 for difference). Furthermore, an adverse risk factor summary was observed among 62% of the children with the highest (upper 5%) BMI levels but among only 54% of children with the highest SF sum levels. Conclusions: BMI is at least as accurate as SF sum in identifying children and adolescents who are at metabolic risk. Because of the training and errors associated with skinfold-thickness measurements, the advantages of BMI should be considered in the design and interpretation of clinical and epidemiologic studies. Am J Clin Nutr 2009; 90: 210-6.
引用
收藏
页码:210 / 216
页数:7
相关论文
共 54 条
[1]  
[Anonymous], R LANG ENV STAT COMP
[2]   HIGH BLOOD-PRESSURE IN THE YOUNG [J].
BERENSON, GS ;
CRESANTA, JL ;
WEBBER, LS .
ANNUAL REVIEW OF MEDICINE, 1984, 35 :535-560
[3]   Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults [J].
Berenson, GS ;
Srinivasan, SR ;
Bao, WH ;
Newman, WP ;
Tracy, RE ;
Wattigney, WA .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (23) :1650-1656
[4]  
Berenson GS., 1980, Cardiovascular risk factors in children: The early natural history of atherosclerosis and essential hypertension
[5]   Body mass index in adolescence in relation to cause-specific mortality: A follow-up of 230,000 Norwegian adolescents [J].
Bjorge, Tone ;
Engeland, Anders ;
Tverdal, Aage ;
Smith, George Davey .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2008, 168 (01) :30-37
[6]   Value of body fat mass vs anthropometric obesity indices in the assessment of metabolic risk factors [J].
Bosy-Westphal, A ;
Geisler, C ;
Onur, S ;
Korth, O ;
Selberg, O ;
Schrezenmeir, J ;
Müller, MJ .
INTERNATIONAL JOURNAL OF OBESITY, 2006, 30 (03) :475-483
[7]   Prediction of body fat in 12-y-old African American and white children: evaluation of methods [J].
Bray, GA ;
DeLany, JP ;
Volaufova, J ;
Harsha, DW ;
Champagne, C .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 76 (05) :980-990
[8]  
Canty A.R., BOOT BOOTSTRAP R S P
[9]   Cadaver studies and their impact on the understanding of human adiposity [J].
Clarys, JP ;
Provyn, S ;
Marfell-Jones, MJ .
ERGONOMICS, 2005, 48 (11-14) :1445-1461
[10]   The utility of body mass index as a measure of body fatness in children and adolescents: Differences by race and gender [J].
Daniels, SR ;
Khoury, PR ;
Morrison, JA .
PEDIATRICS, 1997, 99 (06) :804-807