Bone ingrowth in the presence of particulate polyethylene - Synergy between interface motion and particulate polyethylene in periprosthetic tissue response

被引:17
作者
Bechtold, JE [1 ]
Kubic, V
Soballe, K
机构
[1] Midwest Orthopaed Res Fdn, Orthopaed Biomech Lab, Minneapolis, MN USA
[2] Aarhus Univ Hosp, Dept Paediat Orthopaed, DK-8000 Aarhus C, Denmark
来源
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME | 2002年 / 84B卷 / 06期
关键词
D O I
10.1302/0301-620X.84B6.12111
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We have investigated whether the presence of polyethylene (PE) alone is sufficient to cause an aggressive periprosthetic tissue response, or whether certain mechanical interface conditions can allow bone to grow while in the presence of PE. An experimental implant was loaded in the presence and absence of particulate PE under stable and unstable conditions. Bone with a thin, discontinuous fibrous membrane formed in both groups of stable implants, either in the presence or absence of PE. By contrast, a continuous fibrous membrane consistently formed in both groups of unstable implants. The membrane consisted of loose fibrous connective tissue when PE was absent, and dense connective tissue with macrophages and a synovial lining when PE was present. In this model, if the interface was stable, the presence of PE was not sufficient to prevent the formation of bone or to produce a phagocytic tissue response. Only when the interface was unstable did a fibrous membrane form, and only then in the presence of PE.
引用
收藏
页码:915 / 919
页数:5
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