Vitamin B12: From Deficiency to Biotechnological Solution

被引：5

作者：

Massoud, Ramona ^{[1
]}

Khosravi-Darani, Kianoush ^{[2
]}

Bagheri, Seyed M. H. ^{[3
]}

Mortazavian, Amir M. ^{[3
]}

Sohrabvandi, Sara ^{[2
]}

机构：

[1] Dept Food Res, Stand Org, Tehran, Iran

[2] Shahid Beheshti Univ Med Sci, Fac Nutr Sci & Food Technol, Natl Nutr & Food Technol Res Inst, Res Dept Food Technol, POB 19395-4741, Tehran, Iran

[3] Shahid Beheshti Univ Med Sci, Dept Food Sci & Technol, Natl Nutr & Food Technol Res Inst, Fac Nutr Sci & Food Technol, Tehran, Iran

来源：

CURRENT NUTRITION & FOOD SCIENCE | 2019年 / 15卷 / 04期

关键词：

Biosynthesis; functional food; health effects; propionibacteria; vitamin B-12; anti-microbial compounds; PROPIONIC-ACID BACTERIA; MEVALONATE KINASE; PROPIONIBACTERIUM-ACIDIPROPIONICI; LACTOBACILLUS-ACIDOPHILUS; SUBSTRATE-SPECIFICITY; MICROBIAL-PRODUCTION; SPIRULINA-PLATENSIS; PERNICIOUS-ANEMIA; COBALAMIN; MECHANISM;

D O I：

10.2174/1573401314666171207145429

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Vitamin B-12 production by using propionibacteria and enriching food to produce functional foods is an important subject for researches. Some microorganisms have the potential to produce a wide range of components that are health promoting for human. Among them Propionibacteria has been identified as an effective producer of vitamin B-12 and anti-microbial compounds such as propionic acid for decades. In this study at first, the structure, health beneficial effects and properties of vitamin B-12 as well as scaled up production of vitamin are mentioned. Then biotechnological strategy is described as a solution to overcome vitamin deficiency and production of functional food. Finally, the specification of propionibacteria and its growth condition as well as bacterium ability to produce some other interesting metabolite in human food as byproduct are discussed.

引用

页码：318 / 326

页数：9

共 95 条

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