Natural infection with adeno-associated viruses

被引：0

作者：

Dupressoir, T

Schlehofer, JR

机构：

[1] Inst Biol Lille, CNRS, UMR 8526, F-59021 Lille, France

[2] Deutsch Krebsforschungszentrum, D-6900 Heidelberg, Germany

来源：

ANNALES DE BIOLOGIE CLINIQUE | 1999年 / 57卷 / 06期

关键词：

AAV; parvovirus; infection; oncosuppression; integration; cancer;

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Adeno-associated viruses (AAV) are parvoviruses which exhibit oncosuppressive properties as well as unique characteristics of integration. They have never been associated with human diseases. AAV are thus considered promising vectors for the corrective therapy of various gene defects. In this review, the (possible) consequences of AAV infection for human health, cancer development and recombinant AAV vectors are discussed with respect to recent results on the cellular and molecular targets of AAV infection in humans.

引用

页码：667 / 675

页数：9

共 59 条

[1]

Anderson RJ, 1997, EXP HEMATOL, V25, P256

[2] Human adeno-associated virus type 5 is only distantly related to other known primate helper-dependent parvoviruses [J].