Antioxidant Effect of Grapevine Leaf Extract on the Oxidative Stress Induced by a High-fat Diet in Rats

被引：4
|
作者：
Yu, Qi-Ming [1 ]
Lim, Eun-Ji [1 ]
Choi, Soo-Kyong [1 ]
Seo, Jung-Sook [1 ]
机构：
[1] Yeungnam Univ, Dept Food & Nutr, Gyeongbuk 712749, South Korea
来源：
FOOD SCIENCE AND BIOTECHNOLOGY | 2014年 / 23卷 / 03期
关键词：
grapevine leaf; oxidative stress; antioxidant; high fat; lipid peroxide; VITIS-VINIFERA; RESVERATROL; GLUTATHIONE; LIVER; SUPEROXIDE; CAPACITY; ALCOHOL; PLASMA; LEAVES; HEART;
D O I：
10.1007/s10068-014-0114-4
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
This study was conducted to investigate the effect of grapevine leaf extract (GLE) on the oxidative stress of rats fed a high-fat diet. Rats were divided into six groups: a normal diet with 0% (NC), 1.0% (NG1.0), and 1.5% GLE (NG1.5); and a high-fat diet with 0% (HFC), 1.0% (HFG1.0), and 1.5% GLE (HFG1.5). Treatment with GLE to the high-fat diet reduced lipid peroxide concentrations in plasma and liver compared to those of HFC rats. Total glutathione and GSH/GSSG of the groups with GLE were higher than those of untreated groups. Hepatic glutathione peroxidase, glutathione-S-transferase, and glutathione reductase activities along with catalase and glutathione peroxidase activities in erythrocytes increased after GLE treatment to high-fat diet compared with HFC rats. Hepatic retinol and tocopherol increased in HFG1.5 group compared to those of HFC group. These results indicate that GLE can protect against oxidative stress induced by a high-fat diet in rats.
引用
收藏
页码：849 / 857
页数：9
相关论文
共 50 条
  • [1] Antioxidant effect of grapevine leaf extract on the oxidative stress induced by a high-fat diet in rats
    Qi-Ming Yu
    Eun-Ji Lim
    Soo-Kyong Choi
    Jung-Sook Seo
    Food Science and Biotechnology, 2014, 23 : 849 - 857
  • [2] Effect of red wines with different in vitro antioxidant activity on oxidative stress of high-fat diet rats
    Lauer Macedo, Luciene Fagundes
    Rogero, Marcelo Macedo
    Guimaraes, Jessica Pereira
    Granato, Daniel
    Lobato, Luciana Pereira
    Castro, Inar Alves
    FOOD CHEMISTRY, 2013, 137 (1-4) : 122 - 129
  • [3] The effect of high-fat diet on seizure threshold in rats: Role of oxidative stress
    Alzoubi, Karem H.
    Hasan, Zuhair A.
    Khabour, Omar F.
    Mayyas, Fadia A.
    Al Yacoub, Omar N.
    Banihani, Saleem A.
    Azab, Mohammad A.
    Alrabadi, Nasr
    PHYSIOLOGY & BEHAVIOR, 2018, 196 : 1 - 7
  • [4] Antioxidant potential of barley extract in rats subjected to a high-fat diet
    Zimmermann, Alice Mesquita
    Rivero, Alessandra Coelho
    Bezerra, Aline Sobreira
    Ruviaro, Amanda Roggia
    Ercolani Novack, Mariana Moura
    Noernberg, Jose Laerte
    FOOD SCIENCE AND TECHNOLOGY, 2013, 33 (01): : 167 - 171
  • [5] Beneficial effect of seaweed on high-fat diet-induced oxidative stress and insulin resistance in rats
    Tong, Tao
    Ko, Du-Ok
    Kim, Bo-Sup
    Ham, Kyung-Sik
    Kang, Seong-Gook
    FOOD SCIENCE AND BIOTECHNOLOGY, 2015, 24 (06) : 2185 - 2191
  • [6] Beneficial effect of seaweed on high-fat diet-induced oxidative stress and insulin resistance in rats
    Tao Tong
    Du-Ok Ko
    Bo-Sup Kim
    Kyung-Sik Ham
    Seong-Gook Kang
    Food Science and Biotechnology, 2015, 24 : 2185 - 2191
  • [7] Protective effect of Caralluma fimbriata against high-fat diet induced testicular oxidative stress in rats
    Gujjala, Sudhakara
    Putakala, Mallaiah
    Gangarapu, Venkatanarayana
    Nukala, Srinivasulu
    Bellamkonda, Ramesh
    Ramaswamy, Rajendran
    Desireddy, Saralakumari
    BIOMEDICINE & PHARMACOTHERAPY, 2016, 83 : 167 - 176
  • [8] ANTIOXIDANT EFFECT OF TRITICUM AESTIVIUM (WHEAT GRASS) IN HIGH-FAT DIET-INDUCED OXIDATIVE STRESS IN RABBITS
    Sethi, J.
    Yadav, M.
    Dahiya, K.
    Sood, S.
    Singh, V.
    Bhattacharya, S. B.
    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, 2010, 32 (04): : 233 - 235
  • [9] Moringa oleifera leaf extract ameliorated high-fat diet-induced obesity, oxidative stress and disrupted metabolic hormones
    Azza I. Othman
    Maher A. Amer
    Asmaa S. Basos
    Mohammed A. El-Missiry
    Clinical Phytoscience, 5 (1)
  • [10] Green perilla leaf extract ameliorates long-term oxidative stress induced by a high-fat diet in aging mice
    Edward, Olivet Chiamaka
    Thomas, Shalom Sara
    Cha, Kyung-Ok
    Jung, Hyun-Ah
    Han, Anna
    Cha, Youn-Soo
    NUTRITION RESEARCH AND PRACTICE, 2022, 16 (05) : 549 - 564
12345