PDMS Microchannel Regenerative Peripheral Nerve Interface

被引：0
|
作者：
Musick, Katherine M. [1 ]
Chew, Daniel J. [2 ]
Fawcett, James W. [2 ]
Lacour, Stephanie P. [1 ]
机构：
[1] EPFL STI IMT IBI LSBI, Ctr Neuroprosthet, CH-1015 Lausanne, Switzerland
[2] Univ Cambridge, Cambridge Ctr Brain Repair, Cambridge CB2 0PY, England
来源：
2013 6TH INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING (NER) | 2013年
关键词：
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We have fabricated a soft silicone structure to support the regeneration of a sciatic nerve. The device consists of 70 parallel (120 x 110 mu m(2)) channels through which axons extend and then reconnect to the muscles on the other side of the device. Through histology and electrophysiology, we show that axons grow through the device and functionality of the muscle control is restored. Nerve functionality as demonstrated with stimulated electromyography (EMG) recordings is still intact at 9 months after implantation. Future work on this device will include electrodes for recording and stimulating the regenerating nerve.
引用
收藏
页码：649 / 652
页数：4
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