Preparation of 1,2,4-trisubstituted imidazoles by ammonolysis of N-(2-oxoalkyl)oxazolinium salts

被引:3
作者
John, MP [1 ]
Hermitage, SA [1 ]
Titchmarsh, JR [1 ]
机构
[1] GlaxoSmithKline, Chem Dev Div, Med Res Ctr, Stevenage SG1 2NY, Herts, England
关键词
imidazole; oxazolinium salts; ammonia;
D O I
10.1016/S0040-4039(02)01586-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A variety of aryl and alkyl substituted imidazoles have been prepared by the ring opening of N-(2-oxoalkyl)oxazolinium salts with ammonia. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:6997 / 6999
页数:3
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