Genomic-scale analysis of gene expression in resting and activated T cells

被引:47
作者
Marrack, P
Mitchell, T
Hildeman, D
Kedl, R
Teague, TK
Bender, J
Rees, W
Schaefer, BC
Kappler, J
机构
[1] Natl Jewish Med & Res Ctr, Dept Immunol, Howard Hughes Med Inst, Denver, CO 80206 USA
[2] Univ Colorado, Hlth Sci Ctr, Dept Biochem & Mol Biol, Denver, CO 80206 USA
[3] Univ Colorado, Hlth Sci Ctr, Dept Immunol, Denver, CO 80206 USA
[4] Univ Colorado, Hlth Sci Ctr, Dept Pharmacol, Denver, CO 80206 USA
[5] Univ Colorado, Hlth Sci Ctr, Dept Med, Denver, CO 80206 USA
关键词
D O I
10.1016/S0952-7915(99)00075-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recent advances in gene array technology and isolation of lymphocytes now allow comprehensive analysis of gene expression in many different types of T cells. So far only a few sets of results have been published. However it is already clear that these analyses provide accurate measurements of gene expression in T cells. This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli.
引用
收藏
页码:206 / 209
页数:4
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