Methyl 5-deoxy-alpha and beta-D-xylofuranosides

被引：7

作者：

Moravcova, J

Capkova, J

Stanek, J

Raich, I

机构：

[1] Dept. of Chem. of Natural Compounds, Institute of Chemical Technology, 166 28 Prague

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1997年 / 16卷 / 07期

关键词：

D O I：

10.1080/07328309708005737

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthesized from D-xylose, methyl 5-deoxy-alpha-D-xylofuranoside (1) and methyl 5-deoxy-beta-D-xylofuranoside (2) were obtained in overall yields of 24 and 26 %, respectively. The key step in the synthesis was the separation of an anomeric mixture on a strong anion exchanger in OH- form. NMR data and mass spectra of title compounds 1, 2, methyl 2,3-di-O-acetyl-5-deoxy-alpha-D-xylofuranoside (3), and methyl 2,3-di-O-acetyl-5-deoxy-beta-D-xylofuranoside (4) are discussed. The conformations of 1 and 2 were established from the best fit between calculated and experimental coupling constants using Karplus equation.

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页码：1061 / 1073

页数：13

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