Synthesis of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives via a one-pot four-component reaction

被引：52

作者：

Shaabani, Ahmad ^{[1
]}

Seyyedhamzeh, Mozhdeh ^{[1
]}

Maleki, Ali ^{[1
]}

Behnam, Maryam ^{[1
]}

Rezazadeh, Fahimeh ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 24期

关键词：

Pyrazolo[3,4-b]pyridine-5-carboxamide; Multicomponent reaction; One-pot; 1,3-Diphenyl-1H-pyrazol-5-amine; Diketene; MICROWAVE IRRADIATION; INHIBITORS; ALPHA;

D O I：

10.1016/j.tetlet.2009.03.200

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot four-component reaction of an aliphatic or aromatic amine, diketene, an aromatic aldehyde and 1,3-diphenyl-1H-pyrazol-5-amine in the presence of p-toluenesulfonic acid as a catalyst has been developed. In this reaction, a new class of fully substituted pyrazolo[3,4-b]pyridine-5-carboxamide derivatives is produced under mild reaction conditions and in good yields at ambient temperature. (C) 2009 Published by Elsevier Ltd.

引用

页码：2911 / 2913

页数：3

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