Efficacy of plasmapheresis for the treatment of pure red blood cell aplasia after allogeneic stem cell transplantation

被引：11

作者：

Dellacasa, Chiara Maria ^{[1
]}

D'Ardia, Stefano ^{[2
]}

Allione, Bernardino ^{[2
]}

Aydin, Semra ^{[2
]}

Tassi, Valter ^{[3
]}

Francisci, Tiziana ^{[3
]}

Pecoraro, Clara ^{[4
]}

Busca, Alessandro ^{[1
]}

机构：

[1] AOU Citta Salute & Sci, SSCVD Trapianto Cellule Staminali Allogen, Turin, Italy

[2] AOU Citta Salute & Sci, SC Ematol, Turin, Italy

[3] AOU Citta Salute & Sci, SC Banca Sangue, Turin, Italy

[4] Osped San Giovanni Bosco, SC Immunopatol & Malattie Rare, Turin, Italy

来源：

TRANSFUSION | 2015年 / 55卷 / 12期

关键词：

ERYTHROPOIESIS; ANEMIA;

D O I：

10.1111/trf.13269

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BACKGROUND: Pure red blood cell aplasia (PRCA) is a complication of ABO major-incompatible stem cell transplantation, likely due to the persistence of memory B lymphocytes of recipient origin, which produce hemagglutinins against ABO antigens on donor RBCs. At present no standard of care is established for this complication. CASE REPORT: We report a case of PRCA after allogeneic bone marrow transplantation, successfully treated with plasma exchange (PEX) after failing erythropoietin administration. RESULTS: The patient fully recovered from RBC aplasia. CONCLUSION: This case suggests a role for PEX in the treatment of PRCA after allogeneic stem cell transplantation.

引用

页码：2979 / 2982

页数：4

共 17 条

[1] Incidence and natural history of pure red cell aplasia in major ABO-mismatched haematopoietic cell transplantation [J].

Aung, Fleur M. ;

Lichtiger, Benjamin ;

Bassett, Roland ;

Liu, Ping ;

Alousi, Amin ;

Bashier, Qaiser ;

Ciurea, Stefan O. ;

de Lima, Marcos J. ;

Hosing, Chitra ;

Kebriaei, Partow ;

Nieto, Yago ;

Oran, Betul ;

Parmar, Simrit ;

Qazilbash, Muzaffar ;

Shah, Nina ;

Khouri, Issa ;

Champlin, Richard E. ;

Popat, Uday .

BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (06) :798-805

[2] Mesenchymal stem cells for the treatment of refractory pure red cell aplasia after major ABO-incompatible hematopoietic stem cell transplantation [J].

Fang, Baijun ;

Song, Yongping ;

Li, Ning ;

Li, Jing ;

Han, Qin ;

Zhao, Robert Chunhua .

ANNALS OF HEMATOLOGY, 2009, 88 (03) :261-266

[3]

GMUR JP, 1990, BLOOD, V75, P290

[4] Persistence of recipient plasma cells and anti-donor isohaemagglutinins in patients with delayed donor erythropoiesis after major ABO incompatible non-myeloablative haematopoietic cell transplantation [J].

Griffith, LM ;

McCoy, JP ;

Bolan, CD ;

Stroncek, DF ;

Pickett, AC ;

Linton, GF ;

Lundqvist, A ;

Srinivasan, R ;

Leitman, SF ;

Childs, RW .

BRITISH JOURNAL OF HAEMATOLOGY, 2005, 128 (05) :668-675

[5]

Helbig G, 2005, HAEMATOLOGICA S, V90, P93

[6] Pure red-cell aplasia following major and bi-directional ABO-incompatible allogeneic stem-cell transplantation: recovery of donor-derived erythropoiesis after long-term treatment using different therapeutic strategies [J].

Helbig, Grzegorz ;

Stella-Holowiecka, Beata ;

Wojnar, Jerzy ;

Krawczyk, Malgorzata ;

Krzemien, Slawomira ;

Wojciechowska-Sadus, Maria ;

Markiewicz, Miroslaw ;

Wylezol, Iwona ;

Kopera, Malgorzata ;

Holowiecki, Jerzy .

ANNALS OF HEMATOLOGY, 2007, 86 (09) :677-683

[7] Efficacy and Long-Term Outcome of Treatment for Pure Red Cell Aplasia after Allogeneic Stem Cell Transplantation from Major ABO-Incompatible Donors [J].

Hirokawa, Makoto ;

Fukuda, Takahiro ;

Ohashi, Kazuteru ;

Hidaka, Michihiro ;

Ichinohe, Tatsuo ;

Iwato, Koji ;

Kanamori, Heiwa ;

Murata, Makoto ;

Sakura, Toru ;

Imamura, Masahiro ;

Adachi, Soichi ;

Suzuki, Ritsuro ;

Morishima, Yasuo ;

Sakamaki, Hisashi .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (07) :1026-1032

[8]

MARMONT AM, 1983, EXP HEMATOL, V11, P51

[9] Apheresis therapy for prolonged red cell aplasia after major ABO-mismatched bone marrow transplantation [J].

Ohta, S ;

Yokoyama, H ;

Ise, T ;

Takasawa, K ;

Wada, T ;

Nakao, S ;

Matsuda, T ;

Kobayashi, K .

INTERNAL MEDICINE, 1997, 36 (07) :487-491

[10] ABO-incompatible bone marrow transplantation: a GITMO survey of current practice in Italy and comparison with the literature [J].

Raimondi, R ;

Soli, M ;

Lamparelli, T ;

Bacigalupo, A ;

Arcese, W ;

Belloni, M ;

Rodeghiero, F .

BONE MARROW TRANSPLANTATION, 2004, 34 (04) :321-329

← 1 2 →