Sex differences in stroke: The contribution of coagulation

被引：95

作者：

Roy-O'Reilly, Meaghan ^{[1
]}

McCullough, Louise D. ^{[1
,2
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Sch Med, Farmington, CT 06001 USA

[2] Hartford Hosp, Stroke Ctr, Hartford, CT USA

来源：

EXPERIMENTAL NEUROLOGY | 2014年 / 259卷

关键词：

Cerebral ischemia; Thrombosis; Estrogen; Women; Vasculature; ACUTE ISCHEMIC-STROKE; TISSUE-PLASMINOGEN ACTIVATOR; HORMONE REPLACEMENT THERAPY; NITRIC-OXIDE SYNTHASE; CARDIOVASCULAR-DISEASE RISK; CEREBRAL BLOOD-VESSELS; C-REACTIVE PROTEIN; PERCUTANEOUS CORONARY INTERVENTION; SOLUBLE EPOXIDE HYDROLASE; ORAL-CONTRACEPTIVES RATIO;

D O I：

10.1016/j.expneurol.2014.02.011

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Stroke is now the leading cause of adult disability in the United States. Women are disproportionately affected by stroke. Women increasingly outnumber men in the elderly population, the period of highest risk for stroke. However, there is also a growing recognition that fundamental sex differences are present that contribute to differential ischemic sensitivity. In addition, gonadal hormone exposure can impact coagulation and fibrinolysis, key factors in the initiation of thrombosis. In this review we will discuss sex differences in stroke, with a focus on platelets, vascular reactivity and coagulation. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：16 / 27

页数：12

共 50 条

[21] Systematic review on sex differences for drug use after stroke
Perrier, Julia
Renard, Mathilde
Pariente, Antoine
Bezin, Julien
THERAPIE, 2023, 78 (02): : 213 - 224
[22] Sex Differences and Functional Outcome After Intravenous Thrombolysis
Spaander, Fianne H.
Zinkstok, Sanne M.
Baharoglu, Irem M.
Gensicke, Henrik
Polymeris, Alexandros
Traenka, Christopher
Hametner, Christian
Ringleb, Peter
Curtze, Sami
Martinez-Majander, Nicolas
Aarnio, Karoliina
Nolte, Christian H.
Scheitz, Jan F.
Leys, Didier
Hochart, Anais
Padjen, Visnja
Kagi, Georg
Pezzini, Alessandro
Michel, Patrik
Bill, Olivier
Zini, Andrea
Engelter, Stefan T.
Nederkoorn, Paul J.
STROKE, 2017, 48 (03) : 699 - 703
[23] Sex differences in brain mitochondrial metabolism: influence of endogenous steroids and stroke
Gaignard, P.
Frechou, M.
Liere, P.
Therond, P.
Schumacher, M.
Slama, A.
Guennoun, R.
JOURNAL OF NEUROENDOCRINOLOGY, 2018, 30 (02)
[24] Utilization of Intravenous Tissue Plasminogen Activator for Ischemic Stroke: Are There Sex Differences?
Allen, Norrina B.
Myers, Daniela
Watanabe, Emi
Dostal, Jackie
Sama, Danny
Goldstein, Larry B.
Lichtman, Judith H.
CEREBROVASCULAR DISEASES, 2009, 27 (03) : 254 - 258
[25] Sex Differences in Endovascular Treatment for Stroke: A Population-based Analysis
Zerna, Charlotte
Rogers, Edwin
Rabi, Doreen M.
Demchuk, Andrew M.
Kamal, Noreen
Mann, Balraj
Jeerakathil, Tom
Buck, Brian
Shuaib, Ashfaq
Rempel, Jeremy
Menon, Bijoy K.
Goyal, Mayank
Hill, Michael D.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2021, 48 (04) : 479 - 486
[26] Sex differences in stroke co-morbidities
Branyan, Taylor E.
Sohrabji, Farida
EXPERIMENTAL NEUROLOGY, 2020, 332
[27] Sex differences in miRNA as therapies for ischemic stroke
Sohrabji, Farida
Selvamani, Amutha
NEUROCHEMISTRY INTERNATIONAL, 2019, 127 : 56 - 63
[28] Sex Differences in Stroke in a Sri Lankan Cohort
Ranawaka, Udaya K.
Mettananda, Chamila D.
Nugawela, Miyurangi
Pathirana, Jithmi
Chandrasiri, Jayalath
Jayawardena, Champa
Amarasekara, Deepa
Hettarachchi, Raja
Premawansa, Gayani
Pathmeswaran, Arunasalam
CEREBROVASCULAR DISEASES, 2024,
[29] Sex Differences in Stroke Care and Outcome 2005-2018 Observations From the Swedish Stroke Register
Eriksson, Marie
Asberg, Signild
Sunnerhagen, Katharina Stibrant
von Euler, Mia
STROKE, 2021, 52 (10) : 3233 - 3242
[30] Sex Differences in Functional Outcomes Following Endovascular Treatment for Acute Ischemic Stroke
Momen, Amirah, I
Francis, Troy
Schaafsma, Joanna D.
Rac, Valeria
Baig, Ammar
Pereira, Vitor M.
Pikula, Aleksandra
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2023, 50 (02) : 174 - 181

← 1 2 3 4 5 →