The expression of p53 gene in cervical and ovarian cancer

被引:0
|
作者
Twu, NF [1 ]
Chang, CC [1 ]
Chao, KC [1 ]
Yen, MS [1 ]
机构
[1] Vet Gen Hosp, Dept Obstet & Gynecol, Lab Gynecol Oncol, Taipei, Taiwan
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
One cervical, two ovarian cancer cell lines, 7 cervical and 10 ovarian cancer clinical cell samples were examined the expression of p53 suppression gene and the concerning gene Bar and Fas protein by the method of enzyme-linked immunosorbent assays (ELISA). As the results: p53 gene, Bar or Fas did not express in those three cell lines, neither in 7 cases of cervical cancer patients, but express positive in 8 cases of 10 cases of ovarian cancer patients.
引用
收藏
页码:327 / 330
页数:4
相关论文
共 50 条
  • [21] P53 EXPRESSION, MUTATION, AND ALLELIC DELETION IN OVARIAN-CANCER
    MCMANUS, DT
    YAP, EPH
    MAXWELL, P
    RUSSELL, SEH
    TONER, PG
    MCGEE, JO
    JOURNAL OF PATHOLOGY, 1994, 174 (03): : 159 - 168
  • [22] The Role of p53 Gene in Cervical Carcinogenesis
    Garima
    Pandey S.
    Pandey L.K.
    Saxena A.K.
    Patel N.
    The Journal of Obstetrics and Gynecology of India, 2016, 66 (Suppl 1) : 383 - 388
  • [23] Expression of p53 in epithelial ovarian tumors
    Amanullah, Nihad Abdul Razak
    Poothiode, Usha
    Vilasiniamma, Letha
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2020, 63 (02) : 235 - 240
  • [24] Gene therapy for cancer - p53 tumor-suppressor gene key in ovarian cancer
    Brower, V
    GENETIC ENGINEERING NEWS, 2000, 20 (20): : 1 - +
  • [25] Clinical trials with p53 tumor suppressor gene for p53-mutant ovarian cancer
    Pegram, MD
    Runnebaum, I
    Buekers, T
    Konecny, G
    Karlan, BY
    Chan, D
    Slamon, DJ
    Horowitz, J
    Buller, R
    EUROPEAN JOURNAL OF CANCER, 1999, 35 : S33 - S33
  • [26] Mutations and reduced expression of p53 gene are involved in HPV-independent oncogenesis of cervical cancer
    Yin, Chunhua
    Li, Jiaqi
    He, Quan
    Liu, Sisun
    He, Linsheng
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2017, 10 (04): : 4356 - 4362
  • [27] P53 TUMOR-SUPPRESSOR GENE PROTEIN EXPRESSION IN CERVICAL-CANCER - RELATIONSHIP TO PROGNOSIS
    BREMER, GL
    TIEBOSCHB, ATMG
    VANDERPUTTEN, HWHM
    DEHAAN, J
    ARENDS, JW
    EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1995, 63 (01): : 55 - 59
  • [28] Study of HPV infection, P53 gene mutation and expression in cervical carcinoma
    Li, HF
    Chang, YL
    Li, N
    Yang, SM
    Jia, ZZ
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2001, 28 (02) : 214 - 217
  • [29] Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer
    Dong, Y
    Walsh, MD
    McGuckin, MA
    Cummings, MC
    Gabrielli, BG
    Wright, GR
    Hurst, T
    Khoo, SK
    Parsons, PG
    INTERNATIONAL JOURNAL OF CANCER, 1997, 74 (04) : 407 - 415
  • [30] Expression levels of different p53 and p73 isoforms in ovarian cancer
    Marabese, Mirko
    Marchini, Sergio
    Marrazzo, Eleonora
    Mariani, Pietro
    Cattaneo, Dario
    Fossati, Roldano
    Compagnoni, Anna
    Signorelli, Mauro
    Moll, Ute M.
    Broggini, Massimo
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3499S - 3499S