The prospective role of matrix metalloproteinase-2/9 and transforming growth factor beta 1 in accelerating the progression of hepatocellular carcinoma

被引:6
作者
Chen, Gang [1 ]
Qin, Gui-Hui [2 ]
Dang, Yi-Wu [1 ]
Yang, Jie [2 ]
机构
[1] Guangxi Med Univ, Dept Pathol, Affiliated Hosp 1, Nanning 530021, Peoples R China
[2] Guangxi Med Univ, Sch Pharm, Dept Pharmacol, Nanning 530021, Peoples R China
关键词
CHRONIC LIVER-DISEASE; FIBROSIS; MMP-9;
D O I
10.21037/tcr.2017.02.41
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:S229 / S231
页数:3
相关论文
共 11 条
  • [1] Liver fibrosis
    Bataller, R
    Brenner, DA
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (02) : 209 - 218
  • [2] The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection
    Chen, Rongxin
    Cui, Jiefeng
    Xu, Changde
    Xue, Tongchun
    Guo, Kun
    Gao, Dongmei
    Liu, Yinkun
    Ye, Shenglong
    Ren, Zhenggang
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2012, 19 : S375 - S384
  • [3] Can we stop the progression of chronic liver disease to hepatocellular carcinoma?
    Feitelson, Mark A.
    [J]. TRANSLATIONAL CANCER RESEARCH, 2016, 5 : S794 - S799
  • [4] The rationale for targeting TGF-β in chronic liver diseases
    Giannelli, Gianluigi
    Mikulits, Wolfgang
    Dooley, Steven
    Fabregat, Isabel
    Moustakas, Aristidis
    ten Dijke, Peter
    Portincasa, Piero
    Winter, Peter
    Janssen, Richard
    Leporatti, Stefano
    Herrera, Blanca
    Sanchez, Aranzazu
    [J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2016, 46 (04) : 349 - 361
  • [5] Krstic J, 2014, CELL BIOL, VS1
  • [6] Circulating matrix metalloproteinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C: Comparison with PIIINP and hyaluronic acid
    Leroy, V
    Monier, F
    Bottari, S
    Trocme, C
    Sturm, N
    Hilleret, MN
    Morel, F
    Zarski, JP
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (02) : 271 - 279
  • [7] Association of functional gene polymorphisms of matrix metalloproteinase (MMP)-1, MMP-3 and MMP-9 with the progression of chronic liver disease
    Okamoto, K
    Mimura, K
    Murawaki, Y
    Yuasa, I
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2005, 20 (07) : 1102 - 1108
  • [8] Reciprocal activation between MMP-8 and TGF-β1 stimulates EMT and malignant progression of hepatocellular carcinoma
    Qin, Guihui
    Luo, Min
    Chen, Junze
    Dang, Yiwu
    Chen, Gang
    Li, Li
    Zeng, Jing
    Lu, Yi
    Yang, Jie
    [J]. CANCER LETTERS, 2016, 374 (01) : 85 - 95
  • [9] TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
    Wang, B.
    Hsu, S-H
    Majumder, S.
    Kutay, H.
    Huang, W.
    Jacob, S. T.
    Ghoshal, K.
    [J]. ONCOGENE, 2010, 29 (12) : 1787 - 1797
  • [10] Liver fibrosis: Insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
    Yang, CQ
    Zeisberg, M
    Mosterman, B
    Sudhakar, A
    Yerramalla, U
    Holthaus, K
    Xu, LM
    Eng, F
    Afdhal, N
    Kalluri, R
    [J]. GASTROENTEROLOGY, 2003, 124 (01) : 147 - 159