General method to synthesize disulfide cross-linked peptide-oligonucleotide phosphorothioate conjugates

被引:0
|
作者
Antopolsky, M [1 ]
Azhayeva, E [1 ]
Tengvall, U [1 ]
Azhayev, A [1 ]
机构
[1] Univ Kuopio, Dept Pharmaceut Chem, FIN-70211 Kuopio, Finland
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A disulfide exchange reaction was employed to link eight different peptides to oligonucleotide phosphorothioates resulting into twenty-six various conjugates.
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页码:294 / 297
页数:4
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