Assessment of human antihuman antibodies to eculizumab after long-term treatment in patients with paroxysmal nocturnal hemoglobinuria

被引：14
|
作者：
Hillmen, Peter [1 ]
Muus, Petra [2 ]
Szer, Jeffrey [3 ,4 ]
Hill, Anita [5 ]
Hoechsmann, Britta [6 ,7 ]
Kulasekararaj, Austin
Risitano, Antonio M. [8 ,9 ]
Van Den Neste, Eric [10 ]
Liljeholm, Maria [11 ]
Ebrahim, Kurt S. [12 ]
Bedrosian, Camille L. [13 ]
Gao, Xiang [13 ]
Ames, Donna [13 ]
Socie, Gerard [14 ]
机构：
[1] St James Univ Hosp, Sect Expt Haematol, Level 6,Wellcome Trust Brenner Bldg,Beckett St, Leeds LS9 7TF, W Yorkshire, England
[2] Radboud Univ Nijmegen, Med Ctr, Dept Hematol, NL-6525 ED Nijmegen, Netherlands
[3] Royal Melbourne Hosp, Dept Clin Haematol, Melbourne, Vic, Australia
[4] Royal Melbourne Hosp, BMT Serv, Melbourne, Vic, Australia
[5] Leeds Teaching Hosp, St James Inst Oncol, Dept Haematol, Leeds, W Yorkshire, England
[6] Univ Ulm, Inst Clin Transfus Med & Immunogenet Ulm, Inst Transfus Med, German Red Cross Blood Transfus Serv Baden Wurtte, D-89069 Ulm, Germany
[7] Univ Hosp Ulm, Ulm, Germany
[8] Kings Coll Hosp London, London, England
[9] Univ Naples Federico II, Dipartimento Med Clin & Chirurg, Naples, Italy
[10] Clin Univ UCL St Luc, Dept Hematol, Brussels, Belgium
[11] Univ Umea Hosp, Dept Hematol, S-90185 Umea, Sweden
[12] New England Canc Specialists, Scarborough, ME USA
[13] Alex Pharmaceut Inc, Cheshire, CT USA
[14] Hosp St Louis, AP HP Hematol, Paris, France
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 2016年 / 91卷 / 03期
关键词：
COMPLEMENT INHIBITOR ECULIZUMAB; IMMUNOGENICITY;
D O I：
10.1002/ajh.24280
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：E16 / E17
页数：2
相关论文
共 50 条
  • [1] Long-Term Safety of Sustained Eculizumab Treatment in Patients with Paroxysmal Nocturnal Hemoglobinuria
    Szer, Jeffrey
    Muus, Petra
    Roeth, Alexander
    Elebute, M. O.
    Risitano, Antonio M.
    Schrezenmeier, Hubert
    Maciejewski, Jaroslaw P.
    Urbano-Ispizua, Alvaro
    de Castro, Carlos Manuel, III
    Socie, Gerard
    Brodsky, Robert A.
    BLOOD, 2012, 120 (21)
  • [2] Management of pregnancy in paroxysmal nocturnal hemoglobinuria on long-term eculizumab
    Vekemans, Marie-Christiane
    Lambert, Catherine
    Ferrant, Augustin
    Saussoy, Pascale
    Havelange, Violaine
    Debieve, Frederic
    Van den Neste, Eric
    Michaux, Lucienne
    BLOOD COAGULATION & FIBRINOLYSIS, 2015, 26 (04) : 464 - 466
  • [3] Results of Long-Term Therapy with a Biosimilar of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria
    Kulagin, Alexander D.
    Ptushkin, Vadim V.
    Lukina, Elena A.
    Davydkin, Igor L.
    Korobkin, Alexander V.
    Konstantinova, Tatiana S.
    Komartseva, Elena Yu.
    Minaeva, Natalia V.
    Mitina, Tatiana A.
    Klimova, Olesya U.
    Arshanskaya, Evgeniya G.
    Latyshev, Vitalii D.
    Markova, Oksana A.
    Zuev, Eugene V.
    ACTA HAEMATOLOGICA, 2024,
  • [4] Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria
    Hill, A
    Hillmen, P
    Richards, SJ
    Elebute, D
    Marsh, JC
    Chan, J
    Mojcik, CF
    Rother, RP
    BLOOD, 2005, 106 (07) : 2559 - 2565
  • [5] Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival
    Kelly, Richard J.
    Hill, Anita
    Arnold, Louise M.
    Brooksbank, Gemma L.
    Richards, Stephen J.
    Cullen, Matthew
    Mitchell, Lindsay D.
    Cohen, Dena R.
    Gregory, Walter M.
    Hillmen, Peter
    BLOOD, 2011, 117 (25) : 6786 - 6792
  • [6] Long Term Safety and Efficacy of Sustained Eculizumab Treatment In Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)
    Brodsky, Robert A.
    de Castro, Carlos, III
    Schrezenmeier, Hubert
    Risitano, Antonio M.
    Schubert, Joerg
    Maciejewski, Jaroslaw P.
    Duehrsen, Ulrich
    Luzzatto, Lucio
    Muus, Petra
    Szer, Jeffrey
    Socie, Gerard
    Hillmen, Peter
    BLOOD, 2010, 116 (21) : 1720 - 1721
  • [7] Eculizumab in the Treatment of Paroxysmal Nocturnal Hemoglobinuria
    Hill, Anita
    CLINICAL MEDICINE INSIGHTS-THERAPEUTICS, 2009, 1 : 1467 - 1476
  • [8] Antiphospholipid antibodies in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab
    Helley, D.
    Darnige, L.
    de Latour, R. P.
    Zemori, L.
    Socie, G.
    Fischer, A-M
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 : 624 - 624
  • [9] Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria
    Ninomiya, Haruhiko
    Obara, Naoshi
    Niiori-Onishi, Akiko
    Yokoyama, Yasuhisa
    Sakata-Yanagimoto, Mamiko
    Hasegawa, Yuichi
    Chiba, Shigeru
    CASE REPORTS IN HEMATOLOGY, 2015, 2015
  • [10] Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria
    Hillmen, Peter
    Elebute, Modupe
    Kelly, Richard
    Urbano-Ispizua, Alvaro
    Hill, Anita
    Rother, Russell P.
    Khursigara, Gus
    Fu, Chieh-Lin
    Omine, Mitsuhiro
    Browne, Paul
    Rosse, Wendell
    AMERICAN JOURNAL OF HEMATOLOGY, 2010, 85 (08) : 553 - 559
12345