Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes

被引:76
作者
Rajavel, R. [1 ]
Vadivu, M. Senthil [1 ]
Anitha, C. [1 ]
机构
[1] Periyar Univ, Dept Chem, Salem 636011, Tamil Nadu, India
关键词
Biological activity; 2-Aminobenzaldehyde; Malonoyldihydrazide; Oxovanadium(IV);
D O I
10.1155/2008/583487
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Structural modification of organic molecule has considerable biological relevance. Further, coordination of a biomolecules to the metal ions significantly alters the effectiveness of the biomolecules. In view of the antimicrobial activity ligand [bis-(2-aminobenzaldehyde)] malonoyl dihydrazone], metal complexes with Cu(II), Ni(II), Zn(II) and oxovanadium(IV) have been synthesized and found to be potential antimicrobial agents. An attempt is also made to correlate the biological activities with geometry of the complexes. The complexes have been characterized by elemental analysis, molar conductance, spectra and cyclicvoltammetric measurements. The structural assessment of the complexes has been carried out based on electronic, infrared and molar conductivity values.
引用
收藏
页码:620 / 626
页数:7
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