Distal Ileal Ulcers as Gastrointestinal Manifestation of Waldenstrom Macroglobulinemia

被引：2

作者：

Kantamaneni, Vamsi ^{[1
]}

Gurram, Krishna ^{[2
]}

Khehra, Raman ^{[2
]}

Koneru, Gopala ^{[3
]}

Kulkarni, Abhijit ^{[2
]}

机构：

[1] Allegheny Gen Hosp, Allegheny Hlth Network, Dept Internal Med, Pittsburgh, PA 15212 USA

[2] Allegheny Gen Hosp, Div Gastroenterol, Allegheny Hlth Network, Pittsburgh, PA 15212 USA

[3] Christ Hosp, Cincinnati, OH 45219 USA

来源：

ACG CASE REPORTS JOURNAL | 2019年 / 6卷 / 04期

关键词：

INTESTINAL LYMPHANGIECTASIA; INVOLVEMENT; DISEASE;

D O I：

10.14309/crj.0000000000000058

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Waldenstrom macroglobulinemia (WM) is a neoplastic disorder of the B- cell lymphoid system. A 69-year-old man with WM presented with diarrhea for 6 months. Magnetic resonance enterography showed thickening of the terminal ileum (TI). Colonosocopy with TI intubation showed a single TI ulcer, and small bowel enteroscopy revealed multiple ulcers in the TI. Biopsies from both were negative on hematoxylin and eosin staining. Immunoglobulin M immunofluorescence staining of the ulcers was positive for IgM deposits consistent with WM. After 6 cycles of chemotherapy with bendamustine and rituximab, symptoms resolved.

引用

页数：3

共 18 条

[1]

ASPELIN P, 1989, ACTA RADIOL, V30, P197

[2] MACROGLOBULINAEMIA AND STEATORRHOEA [J].

BRADLEY, J ;

HAWKINS, CF ;

ROWE, DS ;

STANWORTH, DR .

GUT, 1968, 9 (05) :564-+

[3] SMALL-INTESTINAL INVOLVEMENT IN WALDENSTROMS MACROGLOBULINEMIA - CASE-REPORT AND REVIEW OF THE LITERATURE [J].

BRANDT, LJ ;

DAVIDOFF, A ;

BERNSTEIN, LH ;

BIEMPICA, L ;

RINDFLEISCH, B ;

GOLDSTEIN, ML .

DIGESTIVE DISEASES AND SCIENCES, 1981, 26 (02) :174-180

[4] AMYLOIDOSIS AND PLASMA-CELL DYSCRASIAS - GASTROINTESTINAL INVOLVEMENT [J].

CARLSON, HC ;

BREEN, JF .

SEMINARS IN ROENTGENOLOGY, 1986, 21 (02) :128-138

[5] CHLORODEOXYADENOSINE THERAPY OF PATIENTS WITH WALDENSTROM MACROGLOBULINEMIA PREVIOUSLY TREATED WITH FLUDARABINE [J].

DIMOPOULOS, MA ;

WEBER, DM ;

KANTARJIAN, H ;

KEATING, M ;

ALEXANIAN, R .

ANNALS OF ONCOLOGY, 1994, 5 (03) :288-289

[6]

Groves FD, 1998, CANCER-AM CANCER SOC, V82, P1078

[7] MACROGLOBULINEMIA AND INTESTINAL LYMPHANGIECTASIA - A RARE ASSOCIATION [J].

HARRIS, M ;

BURTON, IE ;

SCARFFE, JH .

JOURNAL OF CLINICAL PATHOLOGY, 1983, 36 (01) :30-36

[8] Waldenstrom's macroglobulinemia of the stomach presenting with upper gastrointestinal hemorrhage [J].

Kaila, VL ;

ElNewihi, HM ;

Dreiling, BJ ;

Lynch, CA ;

Mihas, AA .

GASTROINTESTINAL ENDOSCOPY, 1996, 44 (01) :73-75

[9]

KHILNANI MT, 1969, RADIOL CLIN N AM, V7, P43

[10] Waldenstrom's macroglobulinemia: clinical course and prognostic factors in 60 patients - Experience from a single hematology unit [J].

Kyrtsonis, MC ;

Vassilakopoulos, TP ;

Angelopoulou, MK ;

Siakantaris, MP ;

Kontopidou, FN ;

Dimopoulou, MN ;

Boussiotis, V ;

Gribabis, DA ;

Konstantopoulos, K ;

Vaiopoulos, GA ;

Fessas, P ;

Kittas, C ;

Pangalis, GA .

ANNALS OF HEMATOLOGY, 2001, 80 (12) :722-727

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