The structure of TRPC ion channels

被引:28
|
作者
Li, Jian [1 ,2 ]
Zhang, Xu [3 ]
Song, Xiaojing [3 ]
Liu, Rui [3 ]
Zhang, Jin [3 ]
Li, Zongli [4 ]
机构
[1] Gannan Med Univ, Coll Pharmaceut Sci, Ganzhou 341000, Jiangxi, Peoples R China
[2] Ganan Med Univ, Minist Educ, Key Lab Prevent & Treatment Cardiovasc & Cerebrov, Ganzhou 341000, Peoples R China
[3] Nanchang Univ, Sch Basic Med Sci, Nanchang 330031, Jiangxi, Peoples R China
[4] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Howard Hughes Med Inst, Boston, MA 02115 USA
基金
中国国家自然科学基金;
关键词
TRPC; Cryo-EM; CATION CHANNEL; ACTIVATION;
D O I
10.1016/j.ceca.2019.03.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Briefly review the recent structural work of transient receptor potential canonical (TRPC) ion channels by using electron cryo-microscopy (cryo-EM). The high resolution structures of TRPC3, TRPC4, TRPC5 and TRPC6 are discussed.
引用
收藏
页码:25 / 28
页数:4
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