The structure of TRPC ion channels

被引：28
|
作者：
Li, Jian [1 ,2 ]
Zhang, Xu [3 ]
Song, Xiaojing [3 ]
Liu, Rui [3 ]
Zhang, Jin [3 ]
Li, Zongli [4 ]
机构：
[1] Gannan Med Univ, Coll Pharmaceut Sci, Ganzhou 341000, Jiangxi, Peoples R China
[2] Ganan Med Univ, Minist Educ, Key Lab Prevent & Treatment Cardiovasc & Cerebrov, Ganzhou 341000, Peoples R China
[3] Nanchang Univ, Sch Basic Med Sci, Nanchang 330031, Jiangxi, Peoples R China
[4] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Howard Hughes Med Inst, Boston, MA 02115 USA
来源：
CELL CALCIUM | 2019年 / 80卷
基金：
中国国家自然科学基金;
关键词：
TRPC; Cryo-EM; CATION CHANNEL; ACTIVATION;
D O I：
10.1016/j.ceca.2019.03.005
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Briefly review the recent structural work of transient receptor potential canonical (TRPC) ion channels by using electron cryo-microscopy (cryo-EM). The high resolution structures of TRPC3, TRPC4, TRPC5 and TRPC6 are discussed.
引用
收藏
页码：25 / 28
页数：4
相关论文
共 50 条
  • [31] Amphetamines abuse and depression: Focus on TRPC channels
    Fu, You-Peng
    Wang, Yun
    EXPERIMENTAL NEUROLOGY, 2023, 364
  • [32] Regulation of Cardiovascular Functions by the Phosphorylation of TRPC Channels
    Nishida, Motohiro
    Saiki, Shota
    Kitajima, Naoyuki
    Nakaya, Michio
    Sato, Yoji
    Kurose, Hitoshi
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2010, 130 (11): : 1427 - 1433
  • [33] How TRPC Channels Modulate Hippocampal Function
    Gualdani, Roberta
    Gailly, Philippe
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (11) : 1 - 19
  • [34] Integrin Structure and Functional Relation with Ion Channels
    Arcangeli, Annarosa
    Becchetti, Andrea
    INTEGRINS AND ION CHANNELS: MOLECULAR COMPLEXES AND SIGNALING, 2010, 674 : 1 - 7
  • [35] STIM1-dependent membrane insertion of heteromeric TRPC1-TRPC4 channels in response to muscarinic receptor stimulation
    Harada, Keita
    Matsuoka, Hidetada
    Inoue, Masumi
    JOURNAL OF CELL SCIENCE, 2019, 132 (11)
  • [36] Functional characteristics of TRPC4 channels expressed in HEK 293 cells
    Sung, Tae Sik
    Kim, Min Ji
    Hong, Soojin
    Jeon, Jae-Pyo
    Kim, Byung Joo
    Jeon, Ju-Hong
    Kim, Seon Jeong
    So, Insuk
    MOLECULES AND CELLS, 2009, 27 (02) : 167 - 173
  • [37] Electron cryo-microscopy structure of the canonical TRPC4 ion channel
    Vinayagam, Deivanayagabarathy
    Mager, Thomas
    Apelbaum, Amir
    Bothe, Arne
    Merino, Felipe
    Hofnagel, Oliver
    Gatsogiannis, Christos
    Raunser, Stefan
    ELIFE, 2018, 7
  • [38] Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders
    Erac, Yasemin
    Selli, Cigdem
    Kosova, Buket
    Akcali, Kamil C.
    Tosun, Metiner
    AGE, 2010, 32 (02) : 223 - 230
  • [39] TRPC Channel Structure and Properties
    Feng, Shengjie
    TRANSIENT RECEPTOR POTENTIAL CANONICAL CHANNELS AND BRAIN DISEASES, 2017, 976 : 9 - 23
  • [40] Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders
    Yasemin Erac
    Cigdem Selli
    Buket Kosova
    Kamil C. Akcali
    Metiner Tosun
    AGE, 2010, 32 : 223 - 230
12345