Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

被引：164

作者：

Sartelli, Massimo ^{[1
]}

Baiocchi, Gian L. ^{[2
]}

Di Saverio, Salomone ^{[3
]}

Ferrara, Francesco ^{[4
]}

Labricciosa, Francesco M. ^{[5
]}

Ansaloni, Luca ^{[6
]}

Coccolini, Federico ^{[6
]}

Vijayan, Deepak ^{[7
]}

Abbas, Ashraf ^{[8
]}

Abongwa, Hariscine K. ^{[9
]}

Agboola, John ^{[10
]}

Ahmed, Adamu ^{[11
]}

Akhmeteli, Lali ^{[12
]}

Akkapulu, Nezih ^{[13
]}

Akkucuk, Seckin ^{[14
]}

Altintoprak, Fatih ^{[15
]}

Andreiev, Aurelia L. ^{[7
]}

Anyfantakis, Dimitrios ^{[16
]}

Atanasov, Boiko ^{[17
]}

Bala, Miklosh ^{[18
]}

Balalis, Dimitrios ^{[19
]}

Baraket, Oussama ^{[20
]}

Bellanova, Giovanni ^{[21
]}

Beltran, Marcelo ^{[22
]}

Melo, Renato Bessa ^{[23
]}

Bini, Roberto ^{[24
]}

Bouliaris, Konstantinos ^{[25
]}

Brunelli, Daniele ^{[26
]}

Castillo, Adrian ^{[27
]}

Catani, Marco ^{[28
]}

Jusoh, Asri Che ^{[29
]}

Chichom-Mefire, Alain ^{[30
]}

Cocorullo, Gianfranco ^{[31
]}

Coimbra, Raul ^{[32
]}

Colak, Elif ^{[33
]}

Costa, Silvia ^{[34
]}

Das, Koray ^{[35
]}

Delibegovic, Samir ^{[36
]}

Demetrashvili, Zaza ^{[37
]}

Di Carlo, Isidoro ^{[38
]}

Kiseleva, Nadezda ^{[39
]}

El Zalabany, Tamer ^{[40
]}

Faro, Mario ^{[41
]}

Ferreira, Margarida ^{[42
]}

Fraga, Gustavo P. ^{[43
]}

Gachabayov, Mahir ^{[44
]}

Ghnnam, Wagih M. ^{[45
]}

Gimenez Maurel, Teresa ^{[46
]}

Gkiokas, Georgios ^{[47
]}

Gomes, Carlos A. ^{[48
]}

机构：

[1] Macerata Hosp, Dept Surg, Macerata, Italy

[2] Univ Brescia, Dept Clin & Expt Sci, Brescia, Italy

[3] Maggiore Hosp, Emergency Surg, Bologna, Italy

[4] San Carlo Borromeo Hosp, Gen Surg & Polytrauma, Milan, Italy

[5] UNIVPM, Unit Hyg Prevent Med & Publ Hlth, Dept Biomed Sci & Publ Hlth, Ancona, Italy

[6] Bufalini Hosp, Dept Surg, Cesena, Italy

[7] Univ Hosp Birmingham NHS Fdn Trust, Gen Surg, Birmingham, W Midlands, England

[8] Mansoura Univ Hosp, Emergency Surg, Mansoura, Egypt

[9] Maggiore Univ Hosp, Emergency Surg Unit, Parma, Italy

[10] Kwara State Gen Hosp, Surg, Ilorin, Kwara, Nigeria

[11] Ahmadu Bello Univ, Teaching Hosp Zaria, Surg, Zaria, Nigeria

[12] First Univ Clin, Surg, Tbilisi, Georgia

[13] Baskent Univ, Adana Egitim Ve Uygulama Hastanesi, Gen Surg, Adana, Turkey

[14] Mustafa Kemal Univ, Training & Res Hosp, Gen Surg, Antakya, Turkey

[15] Sakarya Univ, Sch Med, Gen Surg, Sakarya, Turkey

[16] Primary Hlth Care Ctr Kissamos, Primary Care, Khania, Greece

[17] Med Univ Plovdiv, UMHAT Eurohosp, Dept Gen Surg, Plovdiv, Bulgaria

[18] Hadassah Med Ctr, Gen Surg, Jerusalem, Israel

[19] Agios Savvas Anticaner Hosp, Surg Dept, Athens, Greece

[20] Hosp Habib Bouguefa Bizerte, Gen Surg, Bizerte, Tunisia

[21] SS Annunziata Hosp, Gen Surg, Taranto, Italy

[22] Hosp San Juan Dios Serena, Surg, La Serena, Chile

[23] Ctr Hosp Sao Joao, Gen Surg, Porto, Portugal

[24] San Giovanni Bosco Hosp, Gen & Emergency Surg, Turin, Italy

[25] Gen Hosp Larissa, Surg Dept, Larisa, Greece

[26] Citta Castello Hosp, Chirurg, Citta Castello, Italy

[27] Univ Calif Los Angeles, Med Ctr, Dept Surg, Torrance, CA 90509 USA

[28] Univ Roma La Sapienza, DEA, Policlin Umberto 1, Rome, Italy

[29] Kuala Krai Hosp, Gen Surg, Kuala Krai, Kelantan, Malaysia

[30] Reg Hosp, Surg & Obstetr Gynaecol, Limbe, Cameroon

[31] Azienda Osped Univ, Policlin Paolo Giaccone, Emergency Surg, Palermo, Italy

[32] Univ Calif San Diego, Trauma Acute Care Surg, San Diego, CA 92103 USA

[33] Samsun Training & Res Hosp, Gen Surg, Samsun, Turkey

[34] EPE, CHVNG E, Surg, Vila Nova de Gaia, Portugal

[35] Ankara Numune Training & Res Hosp, Gen Surg, Adana, Turkey

[36] Univ Clin Ctr Tuzla, Clin Surg, Colorectal Surg, Tuzla, Bosnia & Herceg

[37] Kipshidze Cent Univ Hosp, Surg, Tbilisi, Georgia

[38] Hamad Gen Hosp, Surg, Doha, Qatar

[39] Riga East Univ Hosp Gailezers, Gen & Emergency Surg, Riga, Latvia

[40] Bahrain Def Force Hosp, Gen Surg, Manama, Bahrain

[41] ABC Med Sch, Trauma & Emergency Surg Div, Dept Gen Surg, Santo Andrei, SP, Brazil

[42] Hosp Garcia Orta, Gen Surg, Lisbon, Portugal

[43] Univ Campinas Unicamp, Hosp Clin, Div Trauma Surg, Campinas, SP, Brazil

[44] Vladimir City Clin Hosp Emergency Med, Dept Abdominal Surg, Vladimir, Russia

[45] Mansoura Univ, Fac Med, Dept Mansoura, Gen Surg, Mansoura, Egypt

[46] Hosp Univ Miguel Servet, Cirugia Gen & Aparato Digest, Zaragoza, Spain

[47] Natl & Kapodistrian Univ Athens, Aretaie Univ Hosp, Dept Surg 2, Athens, Greece

[48] Therezinha Jesus Univ Hosp, Surg, Juiz de Fora, Brazil

[49] Univ Hosp Birmingham NHS Fdn Trust, Upper GI Gen Surg, Birmingham, W Midlands, England

[50] Karadeniz Tech Univ, Farabi Hosp, Dept Gen Surg, Trabzon, Turkey

来源：

WORLD JOURNAL OF EMERGENCY SURGERY | 2018年 / 13卷

关键词：

Acute appendicitis; Diagnosis; Management; Surgery; Antibiotics; UNCOMPLICATED ACUTE APPENDICITIS; RANDOMIZED CONTROLLED-TRIALS; COMPUTED-TOMOGRAPHY; INTERVAL APPENDECTOMY; NONOPERATIVE MANAGEMENT; PERCUTANEOUS DRAINAGE; DIAGNOSING APPENDICITIS; ANTIBIOTIC-TREATMENT; GRADING SYSTEM; METAANALYSIS;

D O I：

10.1186/s13017-018-0179-0

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments. Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study. Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%. Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.

引用

页数：10

共 63 条

[1] THE EPIDEMIOLOGY OF APPENDICITIS AND APPENDECTOMY IN THE UNITED-STATES [J].