A randomized controlled trial of the feasibility and preliminary efficacy of a texting intervention on medication adherence in adults prescribed oral anti-cancer agents: study protocol

被引:11
作者
Spoelstra, Sandra L. [1 ]
Given, Charles W. [2 ]
Sikorskii, Alla [3 ]
Coursaris, Constantinos K. [4 ]
Majumder, Atreyee [3 ]
DeKoekkoek, Tracy [1 ]
Schueller, Monica [1 ]
Given, Barbara A. [1 ]
机构
[1] Michigan State Univ, Coll Nursing, E Lansing, MI 48824 USA
[2] Michigan State Univ, Inst Hlth Care Studies, E Lansing, MI USA
[3] Michigan State Univ, Dept Stat & Probabil, E Lansing, MI USA
[4] Michigan State Univ, Dept Telecommun, Informat Studies, E Lansing, MI USA
关键词
cancer; intervention; medication adherence; mHealth; nursing; oral anti-cancer agent; randomized controlled trial; recruitment; text messaging; BEHAVIORAL SKILLS MODEL; OLDER-ADULTS; HEALTH BEHAVIOR; SELF-EFFICACY; INFORMATION; MANAGEMENT; CANCER; SEVERITY; SYMPTOMS; RECOMMENDATIONS;
D O I
10.1111/jan.12714
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
Aim. The aim of this study was to report a study protocol that examines feasibility, preliminary efficacy and satisfaction of a text message intervention on the outcome of medication adherence in adult patients prescribed oral anti-cancer agents. Background. Administration of oral anti-cancer agents occurs in the home setting, requiring patients to self-manage the regimen as prescribed. However, many barriers to medication adherence exist: regimens are often complex, with cycling of two or more medications; side effects of treatment; most cancer patients are older with comorbid conditions and competing demands; and cognitive decline and forgetfulness may occur. Research indicates patients miss nearly one-third of the prescribed oral anti-cancer agent dosages. Text message interventions have been shown to improve medication adherence in chronic conditions other than cancer. However, a majority of those patients were less than 50 years of age and most cancer patients are diagnosed later in life. Design. A two-group randomized controlled trial with repeated measures. Methods. Seventy-five adult patients newly prescribed an oral anti-cancer agent will be recruited (project funded in April 2013) from community cancer centres and a specialty pharmacy. Participants will be randomized to either a control group (n = 25; usual care) or an intervention group (n = 50; usual care plus text messages timed to medication regimen). Outcome measures include: medication adherence, feasibility and satisfaction with the intervention. Data will be collected over 8 weeks: baseline, weekly and exit. Discussion. Standardized text message intervention protocol and detailed study procedures have been developed in this study to improve medication adherence.
引用
收藏
页码:2965 / 2976
页数:12
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